HitPredict

Interactor 1: PHF12 (Q96QT6)
PHD finger protein 12 (PHD factor 1) (Pf1)
Gene: PHF12

Interactor 2: MTA3 (Q9BTC8)
Metastasis-associated protein MTA3
Gene: MTA3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAH~PHD
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1004 Hs			1 594
+	Hs
		296106 PHF12_HUMAN (1-1004): 0: 1360: 100.00		MTA2_HUMAN (1-584): 0: 611: 64.40
+	Hs
		1300624 PHF12_HUMAN (1-1004): 0: 1360: 100.00		RCOR1_HUMAN (148-567): 3.74e-78: 257: 16.63
+	Hs
		1017343 BPTF_HUMAN (43-264): 2.26e-31: 135: 19.28		MTA3_HUMAN (1-594): 0: 724: 100.00
+	Hs
		1255042 CHD5_HUMAN (15-166): 1.47e-20: 100: 16.77		MTA3_HUMAN (1-594): 0: 724: 100.00
+	Mm
		56904 CHD5_MOUSE (5-166): 1.64e-22: 106: 17.54		MTA3_MOUSE (1-586): 0: 683: 94.20
+	Hs
		1017290 BPTF_HUMAN (43-264): 2.26e-31: 135: 19.28		MTA1_HUMAN (1-586): 0: 627: 69.14
+	Hs
		296001 BPTF_HUMAN (43-264): 2.26e-31: 135: 19.28		MTA2_HUMAN (1-584): 0: 611: 64.40
+	Hs
		1031911 CHD5_HUMAN (15-166): 1.47e-20: 100: 16.77		MTA1_HUMAN (1-586): 0: 627: 69.14
+	Hs
		296083 CHD5_HUMAN (15-166): 1.47e-20: 100: 16.77		MTA2_HUMAN (1-584): 0: 611: 64.40
+	Dm
		81419 CHDM_DROME (50-278): 8.02e-29: 127: 16.47		B7Z0T5_DROME (10-586): 1.02e-169: 506: 43.28
+	Hs
		1285378 PF21A_HUMAN (1-241): 3.04e-30: 130: 16.21		RCOR3_HUMAN (150-571): 3.76e-83: 270: 19.03
+	Hs
		1289745 PF21B_HUMAN (3-173): 8.73e-30: 127: 22.22		RCOR3_HUMAN (150-571): 3.76e-83: 270: 19.03
+	Hs
		170419 TIF1A_HUMAN (10-272): 2.06e-32: 138: 18.08		RCOR2_HUMAN (137-573): 9.57e-77: 254: 18.08
+	Hs
		164501 TRI66_HUMAN (23-282): 1.64e-30: 132: 17.03		RCOR1_HUMAN (148-567): 3.74e-78: 257: 16.63
+	Hs
		1285386 PF21A_HUMAN (1-241): 3.04e-30: 130: 16.21		RCOR1_HUMAN (148-567): 3.74e-78: 257: 16.63
+	Hs
		1223938 PF21A_HUMAN (1-241): 3.04e-30: 130: 16.21		RCOR2_HUMAN (137-573): 9.57e-77: 254: 18.08
+	Hs
		1289746 PF21B_HUMAN (3-173): 8.73e-30: 127: 22.22		RCOR1_HUMAN (148-567): 3.74e-78: 257: 16.63
+	Dm
		332872 CHDM_DROME (50-278): 8.02e-29: 127: 16.47		Q9VNF6_DROME (1-70): 5.18e-24: 109: 68.57
+	Hs
		261613 TRI33_HUMAN (33-272): 8.37e-33: 139: 16.47		NCOR1_HUMAN (267-577): 2.53e-09: 62.7: 11.54
+	Ce
		1094912 CHD3_CAEEL (6-278): 1.12e-22: 107: 14.05		Q86S28_CAEEL (6-72): 5.31e-19: 93.1: 44.93