HitPredict

Interactor 1: MAGI1 (Q96QZ7)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3)
Gene: MAGI1

Interactor 2: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24255178
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1491 Hs			1 1088
+	Hs
		325859 MAGI1_HUMAN (1-1491): 0: 756: 100.00		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		1020225 PTN13_HUMAN (227-1419): 7.85e-57: 220: 10.78		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1232910 LNX2_HUMAN (143-717): 3.54e-21: 102: 12.44		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		280078 MPDZ_HUMAN (17-101): 2.83e-15: 84.1: 27.27		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1344970 WWC3_HUMAN (301-430): 3.58e-15: 83.6: 35.37		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1220087 KIBRA_HUMAN (301-430): 4.15e-15: 83.2: 34.04		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1149656 WWC2_HUMAN (291-423): 9.32e-15: 82: 37.78		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1073470 MAGI1_HUMAN (1-1491): 0: 756: 100.00		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Hs
		325709 PTN13_HUMAN (227-1419): 7.85e-57: 220: 10.78		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		280011 MPDZ_HUMAN (17-101): 2.83e-15: 84.1: 27.27		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325937 WWC3_HUMAN (301-430): 3.58e-15: 83.6: 35.37		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325797 KIBRA_HUMAN (301-430): 4.15e-15: 83.2: 34.04		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		125071 WWP2_HUMAN (215-434): 9.36e-15: 82: 29.39		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325775 WWC2_HUMAN (291-423): 9.32e-15: 82: 37.78		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Ce
		88187 D3YT29_CAEEL (16-555): 3.57e-25: 115: 13.64		WARTS_CAEEL (393-1050): 8.43e-135: 432: 35.98
+	Mm
		554913 DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61		KPCE_MOUSE (554-1010): 2.84e-130: 415: 29.92
+	Mm
		933108 DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61		KAPCB_MOUSE (638-1022): 3.87e-133: 409: 31.62
+	Hs
		942348 DLG4_HUMAN (14-112): 3.09e-17: 89.9: 19.23		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Mm
		1143553 DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61		KS6A2_MOUSE (519-973): 2.65e-79: 277: 19.79
+	Mm
		936586 DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61		ROCK2_MOUSE (640-1008): 1.72e-66: 247: 37.17