HitPredict

Interactor 1: MAGI1 (Q96QZ7)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3)
Gene: MAGI1

Interactor 2: AMOL2 (Q9Y2J4)
Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP)
Gene: AMOTL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1491 Hs			1 779
+	Hs
		1119035 MAGI1_HUMAN (1-1491): 0: 756: 100.00		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		1222264 MAGI1_HUMAN (1-1491): 0: 756: 100.00		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Hs
		1300684 MAGI1_HUMAN (1-1491): 0: 756: 100.00		CING_HUMAN (175-776): 2.05e-17: 89.3: 9.97
+	Hs
		1020172 PTN13_HUMAN (227-1419): 7.85e-57: 220: 10.78		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		1021508 DLG1_HUMAN (14-110): 1.24e-15: 84.8: 19.61		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		280045 MPDZ_HUMAN (17-101): 2.83e-15: 84.1: 27.27		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		1118983 KIBRA_HUMAN (301-430): 4.15e-15: 83.2: 34.04		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		280087 MPDZ_HUMAN (17-101): 2.83e-15: 84.1: 27.27		AMOL2_HUMAN (1-779): 1.36e-71: 251: 100.00
+	Hs
		125503 WWP2_HUMAN (215-434): 9.36e-15: 82: 29.39		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		125805 WWP2_HUMAN (215-434): 9.36e-15: 82: 29.39		AMOL2_HUMAN (1-779): 1.36e-71: 251: 100.00
+	Hs
		1020232 PTN13_HUMAN (227-1419): 7.85e-57: 220: 10.78		CING_HUMAN (175-776): 2.05e-17: 89.3: 9.97
+	Mm
		1225208 MPDZ_MOUSE (17-101): 1e-15: 85.6: 27.27		AMOL2_MOUSE (1-779): 2.27e-58: 214: 86.17
+	Mm
		1145448 PTN13_MOUSE (214-1433): 1.14e-22: 108: 11.58		AMOT_MOUSE (1-661): 2.13e-38: 156: 38.02
+	Hs
		280051 MPDZ_HUMAN (17-101): 2.83e-15: 84.1: 27.27		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Hs
		1220065 KIBRA_HUMAN (301-430): 4.15e-15: 83.2: 34.04		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Hs
		125569 WWP2_HUMAN (215-434): 9.36e-15: 82: 29.39		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Mm
		1257405 MPDZ_MOUSE (17-101): 1e-15: 85.6: 27.27		AMOT_MOUSE (1-661): 2.13e-38: 156: 38.02
+	Mm
		1257408 MPDZ_MOUSE (17-101): 1e-15: 85.6: 27.27		AMOL1_MOUSE (1-761): 1.46e-38: 156: 38.96
+	Hs
		1220103 KIBRA_HUMAN (301-430): 4.15e-15: 83.2: 34.04		MYH4_HUMAN (27-765): 3.23e-24: 111: 10.70
+	Mm
		936586 DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61		ROCK2_MOUSE (307-661): 3.25e-12: 72.4: 17.02