Protein: SRS12
Serine/arginine-rich splicing factor 12 (35 kDa SR repressor protein) (SRrp35) (Splicing factor, arginine/serine-rich 13B) (Splicing factor, arginine/serine-rich 19)

Gene: SRS12, SRSF12
Organism: Homo sapiens
Interactions: 132
UniProt ID: Q8WXF0

Gene Ontology (top 5):
GO:0000244 - spliceosomal tri-snRNP complex assembly
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0000395 - mRNA 5'-splice site recognition
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

942840

SRPK2
SRSF protein kinase 2

3

20

High-throughput

0.873

High

442345

RU17
U1 small nuclear ribonucleoprotein 70 kDa

3

19

High-throughput

0.861

High

1040368

TRA2A
Transformer-2 protein homolog alpha

3

18

High-throughput

0.861

High

641867

U2AF2
Splicing factor U2AF 65 kDa subunit

2

20

High-throughput

0.811

High

833938

CLK2
Dual specificity protein kinase CLK2

2

20

High-throughput

0.811

High

834087

CLK3
Dual specificity protein kinase CLK3

2

20

High-throughput

0.811

High

960220

CDK6
Cyclin-dependent kinase 6

1

5

Small-scale

0.735

High

1263452

SRPK1
SRSF protein kinase 1

1

20

High-throughput

0.735

High

71195

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

20

High-throughput

0.691

High

267035

SRS10
Serine/arginine-rich splicing factor 10

1

20

High-throughput

0.691

High

616431

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.691

High

945303

PRR3
Proline-rich protein 3

1

3

High-throughput

0.691

High

952060

SRSF3
Serine/arginine-rich splicing factor 3

1

20

High-throughput

0.691

High

984105

SRS11
Serine/arginine-rich splicing factor 11

1

10

High-throughput

0.691

High

992863

SRSF1
Serine/arginine-rich splicing factor 1

1

20

High-throughput

0.691

High

993783

SRSF4
Serine/arginine-rich splicing factor 4

1

20

High-throughput

0.691

High

1029020

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.691

High

1116414

LARP7
La-related protein 7

1

19

High-throughput

0.691

High

1168917

LN28B
Protein lin-28 homolog B

1

20

High-throughput

0.691

High

1263443

LAR4B
La-related protein 4B

1

20

High-throughput

0.691

High

1263459

LN28A
Protein lin-28 homolog A

1

20

High-throughput

0.691

High

1263475

ZN346
Zinc finger protein 346

1

3

High-throughput

0.691

High

1263482

RBMX2
RNA-binding motif protein, X-linked 2

1

20

High-throughput

0.691

High

1201565

ZCH18
Zinc finger CCCH domain-containing protein 18

3

20

High-throughput

0.667

High

1250962

SNIP1
Smad nuclear-interacting protein 1

3

4

High-throughput

0.667

High

1263481

LC7L2
Putative RNA-binding protein Luc7-like 2

3

10

High-throughput

0.667

High

1263470

NOL12
Nucleolar protein 12

3

0

High-throughput

0.638

High

575122

RL7
Large ribosomal subunit protein uL30

2

6

High-throughput

0.628

High

1092592

KNOP1
Lysine-rich nucleolar protein 1

2

1

High-throughput

0.628

High

1222964

ERF3B
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

2

10

High-throughput

0.628

High

230900

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

10

High-throughput

0.618

High

899528

MGN
Protein mago nashi homolog

1

6

High-throughput

0.618

High

960396

CDK16
Cyclin-dependent kinase 16

1

4

High-throughput

0.618

High

1057184

MELK
Maternal embryonic leucine zipper kinase

1

5

High-throughput

0.618

High

1060582

ZN638
Zinc finger protein 638

1

9

High-throughput

0.618

High

647148

1433T
14-3-3 protein theta

2

20

High-throughput

0.601

High

683581

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.601

High

904922

1433G
14-3-3 protein gamma

2

20

High-throughput

0.601

High

982334

1433F
14-3-3 protein eta

2

20

High-throughput

0.601

High

1043996

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

16

High-throughput

0.575

High

608602

H1T
Histone H1t

2

8

High-throughput

0.574

High

833788

CLK1
Dual specificity protein kinase CLK1

1

20

High-throughput

0.555

High

149112

CTRO
Citron Rho-interacting kinase

1

14

High-throughput

0.553

High

166593

DCLK1
Serine/threonine-protein kinase DCLK1

1

3

High-throughput

0.553

High

181226

NUP42
Nucleoporin NUP42

1

1

High-throughput

0.536

High

281347

RL1D1
Ribosomal L1 domain-containing protein 1

1

5

High-throughput

0.536

High

806943

RS9
Small ribosomal subunit protein uS4

1

3

High-throughput

0.536

High

807457

RS10
Small ribosomal subunit protein eS10

1

1

High-throughput

0.536

High

916728

RS6
Small ribosomal subunit protein eS6

1

4

High-throughput

0.536

High

1040631

KRR1
KRR1 small subunit processome component homolog

1

2

High-throughput

0.536

High

1092867

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

5

High-throughput

0.536

High

1133904

RM02
Large ribosomal subunit protein uL2m

1

7

High-throughput

0.536

High

1231217

H2B3B
Histone H2B type 3-B

1

7

High-throughput

0.536

High

1263444

RENT1
Regulator of nonsense transcripts 1

1

13

High-throughput

0.536

High

1263457

UTP23
rRNA-processing protein UTP23 homolog

1

1

High-throughput

0.536

High

229450

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

12

High-throughput

0.515

High

1263455

COR1B
Coronin-1B

1

12

High-throughput

0.515

High

1263456

LLPH
Protein LLP homolog

1

0

High-throughput

0.513

High

1263468

DAXX
Death domain-associated protein 6

1

0

High-throughput

0.513

High

1263478

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

180393

MAGB2
Melanoma-associated antigen B2

1

8

High-throughput

0.489

High

470478

H2A1
Histone H2A type 1

1

5

High-throughput

0.489

High

485377

GLI4
Zinc finger protein GLI4

1

1

High-throughput

0.489

High

1259599

THAP3
THAP domain-containing protein 3

1

2

High-throughput

0.489

High

1263469

ZBT47
Zinc finger and BTB domain-containing protein 47

1

1

High-throughput

0.489

High

242746

IF2P
Eukaryotic translation initiation factor 5B

1

2

High-throughput

0.481

High

196486

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

1

High-throughput

0.479

High

216952

KIF1C
Kinesin-like protein KIF1C

1

9

High-throughput

0.479

High

233871

HBP1
HMG box-containing protein 1

1

7

High-throughput

0.479

High

237280

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

4

High-throughput

0.479

High

253388

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

6

High-throughput

0.479

High

308931

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

379659

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

598507

NF1
Neurofibromin

1

7

High-throughput

0.479

High

673505

MPIP2
M-phase inducer phosphatase 2

1

1

High-throughput

0.479

High

673612

MPIP3
M-phase inducer phosphatase 3

1

1

High-throughput

0.479

High

876456

AFAD
Afadin

1

9

High-throughput

0.479

High

877816

FOXA1
Hepatocyte nuclear factor 3-alpha

1

5

High-throughput

0.479

High

880795

HDAC4
Histone deacetylase 4

1

9

High-throughput

0.479

High

898687

RL26
Large ribosomal subunit protein uL24

1

3

High-throughput

0.479

High

969887

KIF23
Kinesin-like protein KIF23

1

16

High-throughput

0.479

High

1076900

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

1

High-throughput

0.479

High

1136533

SPD2A
SH3 and PX domain-containing protein 2A

1

6

High-throughput

0.479

High

1153307

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.479

High

1217969

KSR1
Kinase suppressor of Ras 1

1

11

High-throughput

0.479

High

1221601

SMC5
Structural maintenance of chromosomes protein 5

1

11

High-throughput

0.479

High

1235577

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

7

High-throughput

0.479

High

1243665

NAV1
Neuron navigator 1

1

10

High-throughput

0.479

High

1263450

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

8

High-throughput

0.479

High

1263451

TESK2
Dual specificity testis-specific protein kinase 2

1

2

High-throughput

0.479

High

1263460

PKHA5
Pleckstrin homology domain-containing family A member 5

1

20

High-throughput

0.479

High

1263461

KI13B
Kinesin-like protein KIF13B

1

9

High-throughput

0.479

High

1263462

ANLN
Anillin

1

9

High-throughput

0.479

High

1263463

RAD18
E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.479

High

1263474

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

4

High-throughput

0.479

High

1263477

PPM1H
Protein phosphatase 1H

1

1

High-throughput

0.479

High

1263479

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

1

High-throughput

0.479

High

1263480

GAB2
GRB2-associated-binding protein 2

1

10

High-throughput

0.479

High

1136467

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

0

High-throughput

0.458

High

1263453

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

0

High-throughput

0.458

High

1263465

SH3B4
SH3 domain-binding protein 4

1

0

High-throughput

0.458

High

1263476

ZBT21
Zinc finger and BTB domain-containing protein 21

1

0

High-throughput

0.458

High

1263483

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.458

High

757697

IF4A3
Eukaryotic initiation factor 4A-III

1

20

High-throughput

0.445

High

1263473

DDX41
Probable ATP-dependent RNA helicase DDX41

1

14

High-throughput

0.445

High

264369

GGYF1
GRB10-interacting GYF protein 1

1

2

High-throughput

0.437

High

997199

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

7

High-throughput

0.437

High

1022428

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

4

High-throughput

0.437

High

1109679

TBC25
TBC1 domain family member 25

1

4

High-throughput

0.437

High

1139620

DEN4C
DENN domain-containing protein 4C

1

2

High-throughput

0.437

High

1148997

AN34A
Ankyrin repeat domain-containing protein 34A

1

3

High-throughput

0.437

High

1173135

SYDE1
Rho GTPase-activating protein SYDE1

1

8

High-throughput

0.437

High

1189723

MYCPP
C-myc promoter-binding protein

1

2

High-throughput

0.437

High

1197817

PHLB2
Pleckstrin homology-like domain family B member 2

1

15

High-throughput

0.437

High

1253329

F110B
Protein FAM110B

1

1

High-throughput

0.437

High

1256243

DEN1A
DENN domain-containing protein 1A

1

2

High-throughput

0.437

High

1260750

DEP1B
DEP domain-containing protein 1B

1

5

High-throughput

0.437

High

1263445

RL36L
Ribosomal protein eL42-like

1

1

High-throughput

0.437

High

1263447

EDC3
Enhancer of mRNA-decapping protein 3

1

2

High-throughput

0.437

High

1263449

RAB3I
Rab-3A-interacting protein

1

1

High-throughput

0.437

High

1263454

F110A
Protein FAM110A

1

1

High-throughput

0.437

High

1263466

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

1

High-throughput

0.437

High

1263467

CING
Cingulin

1

2

High-throughput

0.437

High

1263471

LIMA1
LIM domain and actin-binding protein 1

1

2

High-throughput

0.437

High

1263472

NGAP
Ras GTPase-activating protein nGAP

1

7

High-throughput

0.437

High

1263484

KCTD3
BTB/POZ domain-containing protein KCTD3

1

1

High-throughput

0.437

High

1263446

ZN689
Zinc finger protein 689

1

0

High-throughput

0.279

Low

1263448

CC140
Coiled-coil domain-containing protein 140

1

0

High-throughput

0.279

Low

1263485

LENEP
Lens epithelial cell protein LEP503

1

0

High-throughput

0.279

Low

316269

NADK
NAD kinase

1

0

High-throughput

0.249

Low

1263458

RTKN
Rhotekin

1

0

High-throughput

0.249

Low

1263464

FA53C
Protein FAM53C

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024