HitPredict - High confidence protein-protein interactions

Method score	Annotation score	Interaction score
0.58	0.90	0.728

Property	Details
Experiments	32494015, 32231289
Identification Methods	electron microscopy 3D single particle reconstruction, cross-linking study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Innexin~Innexin
Common GO terms	GO:0002020 - protease binding GO:0002931 - response to ischemia GO:0005102 - signaling receptor binding GO:0005198 - structural molecule activity GO:0005243 - gap junction channel activity and 25 others more... GO:0005253 - monoatomic anion channel activity GO:0005262 - calcium channel activity GO:0005347 - ATP transmembrane transporter activity GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0005921 - gap junction GO:0006812 - monoatomic cation transport GO:0006816 - calcium ion transport GO:0007267 - cell-cell signaling GO:0015867 - ATP transport GO:0016020 - membrane GO:0022829 - wide pore channel activity GO:0022840 - leak channel activity GO:0032059 - bleb GO:0032730 - positive regulation of interleukin-1 alpha production GO:0032731 - positive regulation of interleukin-1 beta production GO:0032991 - protein-containing complex GO:0033198 - response to ATP GO:0044325 - transmembrane transporter binding GO:0048477 - oogenesis GO:0051015 - actin filament binding GO:0060907 - positive regulation of macrophage cytokine production GO:0097110 - scaffold protein binding GO:0098656 - monoatomic anion transmembrane transport
Homologous interactions	0