HitPredict

Interactor 1: IFIT3 (O14879)
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (CIG49) (ISG-60) (Interferon-induced 60 kDa protein) (IFI-60K) (Interferon-induced protein with tetratricopeptide repeats 4) (IFIT-4) (Retinoic acid-induced gene G protein) (P60) (RIG-G)
Gene: IFIT3

Interactor 2: IFNA5 (P01569)
Interferon alpha-5 (IFN-alpha-5) (Interferon alpha-61) (Interferon alpha-G) (LeIF G)
Gene: IFNA5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26186194
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0051607 - defense response to virus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 490 Hs			1 189
+	Hs
		157400 IFIT3_HUMAN (1-490): 2.07e-117: 355: 100.00		IFN21_HUMAN (1-189): 1.44e-102: 295: 86.77
+	Hs
		157402 IFIT3_HUMAN (1-490): 2.07e-117: 355: 100.00		IFN14_HUMAN (1-189): 2.2e-101: 291: 84.66
+	Hs
		157399 IFIT3_HUMAN (1-490): 2.07e-117: 355: 100.00		IFNA7_HUMAN (1-189): 8.66e-101: 290: 79.89
+	Hs
		157398 IFIT3_HUMAN (1-490): 2.07e-117: 355: 100.00		IFNA2_HUMAN (1-189): 5.25e-96: 278: 83.60
+	Hs
		157428 IFIT3_HUMAN (1-490): 2.07e-117: 355: 100.00		IFNA8_HUMAN (1-189): 2.91e-96: 278: 82.01
+	Hs
		352824 IFIT1_HUMAN (1-453): 1.03e-86: 276: 42.74		IFNA5_HUMAN (1-189): 1.5e-105: 302: 100.00
+	Hs
		352779 IFIT1_HUMAN (1-453): 1.03e-86: 276: 42.74		IFN10_HUMAN (1-189): 2e-103: 296: 82.54
+	Hs
		352798 IFIT1_HUMAN (1-453): 1.03e-86: 276: 42.74		IFN21_HUMAN (1-189): 1.44e-102: 295: 86.77
+	Hs
		352836 IFIT1_HUMAN (1-453): 1.03e-86: 276: 42.74		IFN14_HUMAN (1-189): 2.2e-101: 291: 84.66
+	Hs
		352786 IFIT1_HUMAN (1-453): 1.03e-86: 276: 42.74		IFNA7_HUMAN (1-189): 8.66e-101: 290: 79.89
+	Hs
		456259 IFIT1_HUMAN (1-453): 1.03e-86: 276: 42.74		IFNA8_HUMAN (1-189): 2.91e-96: 278: 82.01