HitPredict

Interactor 1: GCP5 (Q96RT8)
Gamma-tubulin complex component 5 (GCP-5)
Gene: TUBGCP5

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1024 Hs			1 605
+	Hs
		1301506 GCP5_HUMAN (1-1024): 0: 1138: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1355107 GCP4_HUMAN (270-1017): 1.94e-154: 474: 14.64		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1355101 GCP4_HUMAN (270-1017): 1.94e-154: 474: 14.64		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1301493 GCP6_HUMAN (578-1017): 7.59e-85: 303: 22.39		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1287593 GCP3_HUMAN (216-692): 2.22e-60: 225: 11.25		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1311294 GCP2_HUMAN (250-623): 2.18e-59: 222: 13.37		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1301492 GCP6_HUMAN (578-1017): 7.59e-85: 303: 22.39		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1287588 GCP3_HUMAN (216-692): 2.22e-60: 225: 11.25		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1311292 GCP2_HUMAN (250-623): 2.18e-59: 222: 13.37		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		197081 GCP2_HUMAN (250-623): 2.18e-59: 222: 13.37		PRP4_HUMAN (387-594): 6.19e-35: 140: 23.66