HitPredict

Interactor 1: SRPK1 (Q96SB4)
SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)
Gene: SRPK1

Interactor 2: PININ (Q9H307)
Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Desmosome-associated protein) (Domain-rich serine protein) (DRS protein) (DRSP) (Melanoma metastasis clone A protein) (Nuclear protein SDK3) (SR-like protein)
Gene: PNN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 23602568
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005886 - plasma membrane GO:0016607 - nuclear speck
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 655 Hs			1 717
+	Hs
		942945 SRPK2_HUMAN (48-655): 9.43e-136: 415: 57.97		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00
+	Hs
		833972 CLK2_HUMAN (484-653): 2.41e-63: 220: 29.07		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00
+	Hs
		625598 CDK2_HUMAN (414-653): 1.01e-65: 219: 19.43		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00
+	Hs
		834121 CLK3_HUMAN (484-653): 1.02e-60: 216: 28.65		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00
+	Hs
		833818 CLK1_HUMAN (436-654): 8.6e-61: 212: 23.45		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00
+	Hs
		1071723 KS6A2_HUMAN (1-374): 1.21e-78: 266: 14.00		MRCKB_HUMAN (151-471): 3.85e-10: 65.7: 16.67