HitPredict

Interactor 1: MINT (Q96T58)
Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog)
Gene: SPEN

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 0.60 0.682

The method score is based on:

Property Details
Experiments 11331609, 15604093, 24268649
Identification Methods affinity chromatography technology, pull down, two hybrid, nuclear magnetic resonance, surface plasmon resonance, isothermal titration calorimetry
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 2 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 3664
Hs

1 2514
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024