HitPredict

Interactor 1: MPH6 (Q99547)
M-phase phosphoprotein 6
Gene: MPHOSPH6

Interactor 2: EXOS1 (Q9Y3B2)
Exosome complex component CSL4 (Exosome component 1)
Gene: EXOSC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	26496610, 28514442, 24981860, 28877463, 33961781
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000178 - exosome (RNase complex) GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus and 1 others more... GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 160 Hs			1 195
+	Hs
		110633 H3BNT4_HUMAN (19-160): 1.34e-58: 180: 100.00		EXOS1_HUMAN (1-195): 1.33e-103: 297: 100.00
+	Hs
		1046325 MPH6_HUMAN (1-160): 1.95e-67: 203: 100.00		EXOS2_HUMAN (7-174): 3.42e-57: 183: 19.19
+	Hs
		110629 H3BNT4_HUMAN (19-160): 1.34e-58: 180: 100.00		EXOS2_HUMAN (7-174): 3.42e-57: 183: 19.19