HitPredict

Interactor 1: TTC1 (Q99614)
Tetratricopeptide repeat protein 1 (TPR repeat protein 1)
Gene: TTC1

Interactor 2: DNJC7 (Q99615)
DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2)
Gene: DNAJC7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	TPR_1~TPR_11, TPR_1~TPR_16, TPR_1~TPR_8, TPR_11~TPR_8, TPR_16~TPR_8, TPR_8~TPR_8
Common GO terms	GO:0005829 - cytosol GO:0006457 - protein folding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 292 Hs			1 494
+	Hs
		174855 FKBP5_HUMAN (5-273): 9.22e-47: 164: 17.20		OGT1_HUMAN (3-401): 1.62e-31: 130: 13.59
+	Hs
		174814 FKBP4_HUMAN (29-282): 8.06e-45: 159: 18.02		OGT1_HUMAN (3-401): 1.62e-31: 130: 13.59
+	Hs
		174743 PPP5_HUMAN (91-287): 1.25e-38: 143: 23.23		OGT1_HUMAN (3-401): 1.62e-31: 130: 13.59
+	Hs
		684691 FKBP5_HUMAN (5-273): 9.22e-47: 164: 17.20		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		684646 FKBP4_HUMAN (29-282): 8.06e-45: 159: 18.02		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		685025 UN45A_HUMAN (105-274): 2.21e-42: 157: 27.65		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		685029 RPAP3_HUMAN (72-252): 7.36e-41: 151: 24.86		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		279295 FKBP5_HUMAN (5-273): 9.22e-47: 164: 17.20		DNJB5_HUMAN (380-491): 5.82e-19: 90.1: 43.31
+	Hs
		684549 PPP5_HUMAN (91-287): 1.25e-38: 143: 23.23		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Dm
		1366835 Q9VH81_DROME (81-287): 2.84e-39: 145: 19.32		Q9VPN5_DROME (7-171): 3.79e-22: 101: 29.09
+	Hs
		1034936 FKBP5_HUMAN (5-273): 9.22e-47: 164: 17.20		DNJB8_HUMAN (381-482): 1.21e-15: 78.2: 44.35
+	Mm
		1141207 PPP5_MOUSE (91-287): 7.88e-39: 144: 22.22		PPP5_MOUSE (139-260): 3.58e-16: 82.8: 13.93
+	Hs
		1034998 FKBP5_HUMAN (5-273): 9.22e-47: 164: 17.20		RPAP3_HUMAN (2-223): 2.82e-09: 61.6: 11.92
+	Hs
		672793 PPP5_HUMAN (91-287): 1.25e-38: 143: 23.23		CDC27_HUMAN (4-128): 1.63e-15: 81.6: 20.80
+	Hs
		858619 FKBP5_HUMAN (5-273): 9.22e-47: 164: 17.20		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79
+	Dm
		1364913 Q9VEV3_DROME (28-285): 1.05e-38: 138: 45.35		Q9VPY9_DROME (380-494): 6.49e-17: 84: 46.67
+	Hs
		1332490 RPAP3_HUMAN (72-252): 7.36e-41: 151: 24.86		RPAP3_HUMAN (2-223): 2.82e-09: 61.6: 11.92
+	Hs
		174501 TOM70_HUMAN (120-215): 6.68e-14: 73.6: 39.58		OGT1_HUMAN (3-401): 1.62e-31: 130: 13.59
+	Hs
		858598 PPP5_HUMAN (91-287): 1.25e-38: 143: 23.23		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79
+	Hs
		297080 TOM70_HUMAN (120-215): 6.68e-14: 73.6: 39.58		TTC28_HUMAN (1-320): 1.04e-19: 95.1: 15.27