Protein: EXOS3
Exosome complex component RRP40 (Ribosomal RNA-processing protein 40)

Gene: EXOS3, Rrp40
Organism: Drosophila melanogaster
Interactions: 109
UniProt ID: Q8IPX7

Gene Ontology (top 5):
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000956 - nuclear-transcribed mRNA catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1305018

Q9VGZ2
FI06805p

3

11

High-throughput

0.827

High

1177455

Q29QQ9
Ribosomal RNA-processing protein 42

2

12

High-throughput

0.737

High

1305027

Q9VK19
FI07225p

2

12

High-throughput

0.737

High

1305048

Q9VW53
FI01414p

2

13

High-throughput

0.737

High

1305060

Q9W1M9
Exosome complex component RRP4

2

7

High-throughput

0.737

High

1305014

Q9VC93
Exosome complex exonuclease RRP44

3

4

Small-scale

0.633

High

1305002

Q8T4A9
Exosome complex component RRP45

1

13

High-throughput

0.575

High

1305015

EXOSX
Exosome complex component 10 homolog

1

2

High-throughput

0.575

High

1305028

Q9VKJ4
Csl4

1

2

High-throughput

0.575

High

1305070

Q9Y134
RNA helicase

1

4

High-throughput

0.575

High

1265944

DHX15
ATP-dependent RNA helicase DHX15 homolog

1

0

High-throughput

0.546

High

1305016

INT5
Integrator complex subunit 5

1

0

Small-scale

0.458

High

53465

PKN
Serine/threonine-protein kinase N

1

1

High-throughput

0.445

High

1305010

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

1

High-throughput

0.445

High

1305012

Q9VAC4
GEO09167p1

1

1

High-throughput

0.445

High

1305031

Q9VKW8
U6 snRNA-associated Sm-like protein LSm4

1

1

High-throughput

0.445

High

1305044

SMD1
Probable small nuclear ribonucleoprotein Sm D1

1

1

High-throughput

0.445

High

1305049

RUXG
Probable small nuclear ribonucleoprotein G

1

1

High-throughput

0.445

High

1305053

Q9VZ88
AT07585p

1

1

High-throughput

0.445

High

54879

A1Z909
LD11307p

1

0

High-throughput

0.426

High

231840

DKC1
H/ACA ribonucleoprotein complex subunit 4

1

0

High-throughput

0.426

High

235214

HTH
Homeobox protein homothorax

1

0

High-throughput

0.426

High

262864

TENM
Teneurin-m

1

0

High-throughput

0.426

High

426699

HP1
Heterochromatin protein 1

1

0

High-throughput

0.426

High

561790

MODU
DNA-binding protein modulo

1

0

High-throughput

0.426

High

654864

MA205
205 kDa microtubule-associated protein

1

0

High-throughput

0.426

High

875530

PTPS
6-pyruvoyl tetrahydrobiopterin synthase

1

0

High-throughput

0.426

High

1050896

SSRP1
FACT complex subunit Ssrp1

1

0

High-throughput

0.426

High

1052554

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

0

High-throughput

0.426

High

1196567

Q4V5H1
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.426

High

1264885

Q7K1Q7
Ribosome assembly factor mrt4

1

0

High-throughput

0.426

High

1273686

Q7PLL3
Eukaryotic initiation factor 4B

1

0

High-throughput

0.426

High

1303647

Q8IN95
Nuclear migration protein nudC

1

0

High-throughput

0.426

High

1304996

SPT16
FACT complex subunit spt16

1

0

High-throughput

0.426

High

1304997

Q8MMD2
Epidermal growth factor receptor pathway substrate clone 15, isoform B

1

0

High-throughput

0.426

High

1304999

Q8SWS7
Nucleolar protein 12

1

0

High-throughput

0.426

High

1305000

Q8SXM8
Lysine--tRNA ligase

1

0

High-throughput

0.426

High

1305004

DYLT
Dynein light chain Tctex-type

1

0

High-throughput

0.426

High

1305017

Y6693
J domain-containing protein CG6693

1

0

High-throughput

0.426

High

1305022

Q9VHT5
Large ribosomal subunit protein uL1m

1

0

High-throughput

0.426

High

1305023

SMD2
Probable small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.426

High

1305026

RAGP1
Ran GTPase-activating protein

1

0

High-throughput

0.426

High

1305029

PIWI
Protein piwi

1

0

High-throughput

0.426

High

1305034

RUXE
Probable small nuclear ribonucleoprotein E

1

0

High-throughput

0.426

High

1305036

Q9VMM7
FI04466p

1

0

High-throughput

0.426

High

1305039

Q9VPM0
GH06023p

1

0

High-throughput

0.426

High

1305046

PYRG
CTP synthase

1

0

High-throughput

0.426

High

1305050

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

1305054

Q9VZC8
GEO12024p1

1

0

High-throughput

0.426

High

1305055

THUM1
THUMP domain-containing protein 1 homolog

1

0

High-throughput

0.426

High

1305059

Q9W1M6
Regulatory protein zeste

1

0

High-throughput

0.426

High

1305061

Q9W224
Novel spermatogenesis regulator, isoform A

1

0

High-throughput

0.426

High

1305064

ZN593
Zinc finger protein 593 homolog

1

0

High-throughput

0.426

High

1305065

Q9W4J4
GM14292p

1

0

High-throughput

0.426

High

1305066

DDB1
DNA damage-binding protein 1

1

0

High-throughput

0.426

High

1305067

Q9XZ57
Eb1, isoform E

1

0

High-throughput

0.426

High

1305069

SYQ
Probable glutamine--tRNA ligase

1

0

High-throughput

0.426

High

1305071

X2JCC3
poly(A)-specific ribonuclease

1

0

High-throughput

0.426

High

1305001

WDR55
WD repeat-containing protein 55 homolog

1

4

High-throughput

0.407

High

1305005

EBI
F-box-like/WD repeat-containing protein ebi

1

3

High-throughput

0.407

High

1305007

WDS
Protein will die slowly

1

3

High-throughput

0.407

High

1305008

RU2A
Probable U2 small nuclear ribonucleoprotein A'

1

1

High-throughput

0.407

High

1305024

Q9VIH1
CG9273 protein

1

1

High-throughput

0.407

High

1305030

WDR12
Ribosome biogenesis protein WDR12 homolog

1

3

High-throughput

0.407

High

1305051

Q9VYQ9
Pleiotropic regulator 1

1

3

High-throughput

0.407

High

1305058

INT1
Integrator complex subunit 1

1

0

Small-scale

0.249

Low

53133

A1Z7K8
AaRS-interacting multifunctional protein 1

1

0

High-throughput

0.232

Low

54972

A1Z917
PiggyBac transposable element-derived protein domain-containing protein

1

0

High-throughput

0.232

Low

56837

A1ZAK3
Protein DEK

1

0

High-throughput

0.232

Low

231986

O44226
Elongin-B

1

0

High-throughput

0.232

Low

356793

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

0

High-throughput

0.232

Low

828082

LA
La protein homolog

1

0

High-throughput

0.232

Low

847872

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.232

Low

925802

SET
Protein SET

1

0

High-throughput

0.232

Low

1019498

AP2A
AP-2 complex subunit alpha

1

0

High-throughput

0.232

Low

1052413

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.232

Low

1195951

Q4QQ70
IP09819p

1

0

High-throughput

0.232

Low

1261388

Q7JQT8
LD41464p

1

0

High-throughput

0.232

Low

1264021

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.232

Low

1264265

Q7K0L8
FLICE-associated huge protein, isoform A

1

0

High-throughput

0.232

Low

1302933

Q8IHH3
AT01055p

1

0

High-throughput

0.232

Low

1304995

Q8IQI3
Uncharacterized protein, isoform B

1

0

High-throughput

0.232

Low

1304998

SHEP
Protein alan shepard

1

0

High-throughput

0.232

Low

1305003

ACPM
Acyl carrier protein, mitochondrial

1

0

High-throughput

0.232

Low

1305006

NASP
Nuclear autoantigenic sperm protein homolog

1

0

High-throughput

0.232

Low

1305009

NOP10
H/ACA ribonucleoprotein complex subunit 3

1

0

High-throughput

0.232

Low

1305011

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.232

Low

1305013

Q9VBT1
CHK kinase-like domain-containing protein

1

0

High-throughput

0.232

Low

1305019

Q9VHN4
GH14121p

1

0

High-throughput

0.232

Low

1305020

RM19
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.232

Low

1305021

Q9VHR5
Veneno

1

0

High-throughput

0.232

Low

1305025

BERO
UPAR/Ly6 domain-containing protein bero

1

0

High-throughput

0.232

Low

1305032

Q9VL60
RE01590p

1

0

High-throughput

0.232

Low

1305033

Q9VLB7
Rab GDP dissociation inhibitor

1

0

High-throughput

0.232

Low

1305035

Q9VM14
dihydrolipoyllysine-residue acetyltransferase

1

0

High-throughput

0.232

Low

1305037

Q9VNZ3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.232

Low

1305038

RM10
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.232

Low

1305040

Q9VQS4
Spindly

1

0

High-throughput

0.232

Low

1305041

DBR1
Lariat debranching enzyme

1

0

High-throughput

0.232

Low

1305042

QTRT2
Queuine tRNA-ribosyltransferase accessory subunit 2

1

0

High-throughput

0.232

Low

1305043

Q9VT38
GH03795p

1

0

High-throughput

0.232

Low

1305045

RM39
Large ribosomal subunit protein mL39

1

0

High-throughput

0.232

Low

1305047

Q9VVF8
Uncharacterized protein, isoform A

1

0

High-throughput

0.232

Low

1305052

Q9VYT3
FI23714p1

1

0

High-throughput

0.232

Low

1305056

SAHH2
Adenosylhomocysteinase-like 1

1

0

High-throughput

0.232

Low

1305057

Q9W108
FI01540p

1

0

High-throughput

0.232

Low

1305062

Q9W258
Babos, isoform A

1

0

High-throughput

0.232

Low

1305063

Q9W3J4
LD35215p

1

0

High-throughput

0.232

Low

1305068

Q9Y0Y5
Coatomer subunit epsilon

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025