Interactor 1: GFI1 (Q99684)
Zinc finger protein Gfi-1 (Growth factor independent protein 1) (Zinc finger protein 163)
Gene: GFI1

Interactor 2: PRDM5 (Q9NQX1)
PR domain zinc finger protein 5 (EC 2.1.1.-) (PR domain-containing protein 5)
Gene: PRDM5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.781

The method score is based on:

Property Details
Experiments 17636019, 19506020
Identification Methods affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-C2H2~zf-C2H2, zf-C2H2~zf-met
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
and 4 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 422
Hs

1 630
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Last updated: 15 Jul 2024