Protein: TIPRL
TIP41-like protein (Putative MAPK-activating protein PM10) (Type 2A-interacting protein) (TIP)

Gene: TIPRL
Organism: Homo sapiens
Interactions: 60
UniProt ID: O75663

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0005829 - cytosol
GO:0031929 - TOR signaling
GO:0032515 - negative regulation of phosphoprotein phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

272423

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

5

6

Small-scale

0.927

High

135322

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

5

7

Small-scale

0.927

High

272428

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

3

5

Small-scale

0.855

High

272426

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

2

5

Small-scale

0.812

High

272416

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

2

0

High-throughput

0.608

High

226071

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

272418

CCNF
Cyclin-F

2

0

High-throughput

0.559

High

272429

IGBP1
Immunoglobulin-binding protein 1

1

1

Small-scale

0.515

High

272431

CUL3
Cullin-3

1

0

High-throughput

0.513

High

272449

PTN18
Tyrosine-protein phosphatase non-receptor type 18

1

0

High-throughput

0.513

High

272427

DYLT1
Dynein light chain Tctex-type 1

1

1

High-throughput

0.489

High

272444

DYT2B
Dynein light chain Tctex-type protein 2B

1

1

High-throughput

0.489

High

272410

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

160292

AURKA
Aurora kinase A

1

1

High-throughput

0.479

High

201146

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

1

Small-scale

0.479

High

272419

YAP1
Transcriptional coactivator YAP1

1

1

High-throughput

0.479

High

272425

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.479

High

272450

WWTR1
WW domain-containing transcription regulator protein 1

1

1

High-throughput

0.479

High

272405

UFL1
E3 UFM1-protein ligase 1

1

0

Small-scale

0.460

High

272406

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

272411

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

272412

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

272424

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

272432

OZF
Zinc finger protein OZF

1

0

High-throughput

0.458

High

272435

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

272438

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

272439

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

272443

DNJA4
DnaJ homolog subfamily A member 4

1

0

High-throughput

0.458

High

272446

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.458

High

272447

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.458

High

272448

OPTN
Optineurin

1

0

High-throughput

0.458

High

272451

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

272453

CCD39
Coiled-coil domain-containing protein 39

1

0

High-throughput

0.458

High

272433

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

272404

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.437

High

272422

RAB25
Ras-related protein Rab-25

1

1

High-throughput

0.437

High

272430

DUS8
Dual specificity protein phosphatase 8

1

1

High-throughput

0.437

High

272434

RHDF2
Inactive rhomboid protein 2

1

1

High-throughput

0.437

High

272442

RHBL4
Rhomboid-related protein 4

1

1

High-throughput

0.437

High

272408

PRIO
Major prion protein

1

0

High-throughput

0.426

High

272441

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.426

High

272452

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

5

0

Small-scale

0.376

High

272407

FUCO
Tissue alpha-L-fucosidase

2

0

High-throughput

0.328

High

272445

ITLN1
Intelectin-1

2

0

High-throughput

0.328

High

56498

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

2

0

High-throughput

0.305

High

64037

AQ12B
Aquaporin-12B

1

0

High-throughput

0.279

Low

272420

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

0

High-throughput

0.279

Low

272454

LMBL1
Lethal(3)malignant brain tumor-like protein 1

1

0

High-throughput

0.279

Low

100318

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

165803

KDM6B
Lysine-specific demethylase 6B

1

0

Small-scale

0.249

Low

272409

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

272413

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

272414

ZKSC1
Zinc finger protein with KRAB and SCAN domains 1

1

0

High-throughput

0.249

Low

272415

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

272417

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

272436

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

272437

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

272440

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

0

High-throughput

0.249

Low

272455

MAFB
Transcription factor MafB

1

0

High-throughput

0.249

Low

272421

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.213

Low


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Last updated: 15 Jul 2024