HitPredict

Interactor 1: Q8IRD3 (Q8IRD3)
Glutathione peroxidase
Gene: Gtpx

Interactor 2: THIO2 (Q9V429)
Thioredoxin-2 (DmTrx-2)
Gene: Trx2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006979 - response to oxidative stress
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 238 Dm			1 106
+	Dm
		1306110 Q8IRD3_DROME (1-238): 1.35e-141: 397: 100.00		PDIA6_DROME (3-94): 5.93e-27: 104: 18.09
+	At
		235322 GPX6_ARATH (42-238): 1.17e-96: 283: 49.75		TRXH1_ARATH (2-106): 3.44e-35: 117: 39.25
+	So
		200668 GPX4_SPIOL (72-238): 3.58e-89: 262: 54.49		TRXM_SPIOL (3-106): 4.64e-37: 124: 37.14
+	At
		147065 GPX2_ARATH (77-238): 2.34e-86: 255: 56.17		TRXH1_ARATH (2-106): 3.44e-35: 117: 39.25
+	Sc
		652873 GPX2_YEAST (79-238): 3.88e-75: 226: 42.86		TRX2_YEAST (1-106): 5.74e-37: 122: 44.34
+	Hs
		566810 GPX7_HUMAN (82-238): 9.83e-73: 221: 36.94		PDIA4_HUMAN (3-105): 4.83e-26: 102: 22.02