Protein: TRX2
Thioredoxin-2 (Thioredoxin II) (TR-II) (Thioredoxin-1)

Gene: TRX2
Organism: Saccharomyces cerevisiae S288C
Interactions: 95
UniProt ID: P22803

Gene Ontology (top 5):
GO:0000011 - vacuole inheritance
GO:0000103 - sulfate assimilation
GO:0000139 - Golgi membrane
GO:0000324 - fungal-type vacuole
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

652865

TSA1
Peroxiredoxin TSA1

5

20

Small-scale

0.930

High

652856

TRXB1
Thioredoxin reductase 1

3

14

Small-scale

0.835

High

646584

TRX1
Thioredoxin-1

3

11

Small-scale

0.821

High

652872

AHP1
Peroxiredoxin AHP1

2

7

Small-scale

0.815

High

652882

MSRA
Peptide methionine sulfoxide reductase

2

5

Small-scale

0.812

High

652898

TSA2
Peroxiredoxin TSA2

2

20

Small-scale

0.754

High

613740

MET16
Phosphoadenosine phosphosulfate reductase

1

1

Small-scale

0.751

High

543855

SSB1
Ribosome-associated molecular chaperone SSB1

3

7

Small-scale

0.633

High

652893

NOP3
Serine/arginine

1

1

High-throughput

0.618

High

652870

FRMSR
Free methionine-R-sulfoxide reductase

2

1

Small-scale

0.600

High

652850

TRX2
Thioredoxin-2

1

8

High-throughput

0.590

High

652859

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.586

High

392252

HSP82
ATP-dependent molecular chaperone HSP82

2

6

Small-scale

0.584

High

578872

HSC82
ATP-dependent molecular chaperone HSC82

2

6

Small-scale

0.584

High

652888

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

4

High-throughput

0.584

High

652895

ULP1
Ubiquitin-like-specific protease 1

2

2

High-throughput

0.576

High

523094

HSP71
Heat shock protein SSA1

2

3

Small-scale

0.571

High

525954

HSP72
Heat shock protein SSA2

2

3

Small-scale

0.571

High

477514

MYO1
Myosin-1

1

2

Small-scale

0.552

High

652900

RIX7
Ribosome biogenesis ATPase RIX7

1

8

High-throughput

0.536

High

652858

DPH2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

1

2

High-throughput

0.515

High

652885

6P21
6-phosphofructo-2-kinase 1

1

2

High-throughput

0.515

High

652906

GST2
Glutathione S-transferase 2

1

8

High-throughput

0.515

High

602109

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.513

High

652886

MAD2
Mitotic spindle checkpoint component MAD2

1

0

High-throughput

0.513

High

616386

SEC18
Vesicular-fusion protein SEC18

1

9

Small-scale

0.501

High

626470

AP1
AP-1-like transcription factor YAP1

1

1

Small-scale

0.501

High

652864

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

1

High-throughput

0.494

High

652887

PXA1
Peroxisomal long-chain fatty acid import protein 2

1

1

High-throughput

0.494

High

652884

RIC1
Guanine nucleotide exchange factor subunit RIC1

1

0

High-throughput

0.493

High

364338

CDK1
Cyclin-dependent kinase 1

1

4

High-throughput

0.479

High

409944

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

434839

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

502859

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.479

High

536078

ARF1
ADP-ribosylation factor 1

1

2

Small-scale

0.479

High

618937

IRA2
Inhibitory regulator protein IRA2

1

1

High-throughput

0.479

High

646299

RAD53
Serine/threonine-protein kinase RAD53

1

4

High-throughput

0.479

High

649561

KCC2
Calcium/calmodulin-dependent protein kinase II

1

2

High-throughput

0.479

High

652852

BPH1
Beige protein homolog 1

1

10

High-throughput

0.479

High

652853

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

652854

CDC48
Cell division control protein 48

1

8

High-throughput

0.479

High

652855

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

652857

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

652861

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.479

High

652863

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

652871

GBLP
Small ribosomal subunit protein RACK1

1

9

Small-scale

0.479

High

652873

GPX2
Glutathione peroxidase-like peroxiredoxin 2

1

4

Small-scale

0.479

High

652877

RPN10
26S proteasome regulatory subunit RPN10

1

2

High-throughput

0.479

High

652878

UME6
Transcriptional regulatory protein UME6

1

1

High-throughput

0.479

High

652879

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

652880

GPB2
Guanine nucleotide-binding protein subunit beta 2

1

1

High-throughput

0.479

High

652889

MOG1
Nuclear import protein MOG1

1

2

High-throughput

0.479

High

652890

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

652894

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

652896

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

652897

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

652901

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.479

High

652902

GPB1
Guanine nucleotide-binding protein subunit beta 1

1

1

High-throughput

0.479

High

652904

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.479

High

652905

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.479

High

149594

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

383526

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

394248

EF1A
Elongation factor 1-alpha

1

0

Small-scale

0.458

High

433457

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

435781

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

504045

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

518209

IF4A
ATP-dependent RNA helicase eIF4A

1

0

Small-scale

0.458

High

652866

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

652867

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

652868

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

652869

SRX1
Sulfiredoxin

1

0

Small-scale

0.458

High

652874

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

652891

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

652899

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

652907

LAS17
Proline-rich protein LAS17

1

0

Small-scale

0.458

High

358118

ADH1
Alcohol dehydrogenase 1

1

2

Small-scale

0.445

High

359151

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

10

Small-scale

0.445

High

453899

IF4E
Eukaryotic translation initiation factor 4E

1

1

Small-scale

0.445

High

652862

HSP78
Heat shock protein 78, mitochondrial

1

5

High-throughput

0.445

High

652881

DLD3
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD3

1

1

Small-scale

0.445

High

652883

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

652908

SET6
Potential protein lysine methyltransferase SET6

1

1

High-throughput

0.445

High

360947

CCPR
Cytochrome c peroxidase, mitochondrial

1

5

Small-scale

0.437

High

617970

IRA1
Inhibitory regulator protein IRA1

1

1

High-throughput

0.437

High

652860

SC61A
Protein transport protein SEC61

1

2

High-throughput

0.437

High

652875

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

1

High-throughput

0.437

High

652903

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

652851

SWI4
Regulatory protein SWI4

1

0

High-throughput

0.426

High

427540

RLA1
Large ribosomal subunit protein P1A

1

0

High-throughput

0.282

High

506362

NFT1
ABC transporter NFT1

1

0

High-throughput

0.282

High

652876

AIM46
Altered inheritance of mitochondria protein 46, mitochondrial

1

0

High-throughput

0.279

Low

94536

STE2
Pheromone alpha factor receptor

1

0

High-throughput

0.251

Low

506385

YK104
Putative uncharacterized protein YKR104W

1

0

High-throughput

0.251

Low

652892

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025