Interactor 1: M3K3 (Q99759)
Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)
Gene: MAP3K3

Interactor 2: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 33571521
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PB1~Pkinase, Pkinase~Pkinase, Pkinase~Pkinase_C
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0035556 - intracellular signal transduction
GO:0046872 - metal ion binding
and 1 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Hs

1 1088
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Last updated: 15 Jul 2024