Protein: SKI2
Antiviral helicase SKI2 (EC 3.6.4.13) (Superkiller protein 2)

Gene: SKI2
Organism: Saccharomyces cerevisiae S288C
Interactions: 99
UniProt ID: P35207

Gene Ontology (top 5):
GO:0000956 - nuclear-transcribed mRNA catabolic process
GO:0003677 - DNA binding
GO:0003724 - RNA helicase activity
GO:0003729 - mRNA binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

609051

SKI3
Superkiller protein 3

7

7

Small-scale

0.970

High

763849

SKI8
Antiviral protein SKI8

7

20

Small-scale

0.967

High

763823

MAK5
ATP-dependent RNA helicase MAK5

2

16

High-throughput

0.759

High

763860

SKI7
Superkiller protein 7

5

4

Small-scale

0.711

High

763850

HAS1
ATP-dependent RNA helicase HAS1

1

17

High-throughput

0.665

High

763855

RRP45
Exosome complex component RRP45

4

16

High-throughput

0.633

High

763821

GBLP
Small ribosomal subunit protein RACK1

1

20

High-throughput

0.618

High

763827

RRP4
Exosome complex component RRP4

1

11

High-throughput

0.618

High

763842

RS12
Small ribosomal subunit protein eS12

1

3

High-throughput

0.618

High

763846

CSL4
Exosome complex component CSL4

1

3

High-throughput

0.618

High

763859

RRP40
Exosome complex component RRP40

1

4

High-throughput

0.618

High

523561

HSP71
Heat shock protein SSA1

2

15

High-throughput

0.601

High

544403

SSB1
Ribosome-associated molecular chaperone SSB1

2

14

High-throughput

0.601

High

645360

XRN1
5'-3' exoribonuclease 1

2

5

High-throughput

0.601

High

672869

RRP43
Exosome complex component RRP43

2

3

High-throughput

0.601

High

763831

SNU13
13 kDa ribonucleoprotein-associated protein

1

10

High-throughput

0.595

High

434988

RS3
Small ribosomal subunit protein uS3

2

4

Small-scale

0.571

High

763825

RS20
Small ribosomal subunit protein uS10

2

5

Small-scale

0.571

High

763826

SSZ1
Ribosome-associated complex subunit SSZ1

2

6

High-throughput

0.571

High

763841

MTR3
Exosome complex component MTR3

2

1

High-throughput

0.558

High

526361

HSP72
Heat shock protein SSA2

1

15

High-throughput

0.536

High

763843

RL4B
Large ribosomal subunit protein uL4B

1

5

High-throughput

0.536

High

763861

RS10A
Small ribosomal subunit protein eS10A

2

5

Small-scale

0.521

High

751370

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

4

High-throughput

0.515

High

763829

STM1
Suppressor protein STM1

1

1

High-throughput

0.515

High

763844

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

2

High-throughput

0.515

High

763866

YRA1
RNA annealing protein YRA1

1

14

High-throughput

0.515

High

763820

YKC3
Uncharacterized protein YKL023W

1

0

High-throughput

0.493

High

763851

ENT5
Epsin-5

1

0

High-throughput

0.493

High

149686

RS9A
Small ribosomal subunit protein uS4A

1

6

High-throughput

0.479

High

432537

RL7A
Large ribosomal subunit protein uL30A

1

4

High-throughput

0.479

High

436372

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

7

High-throughput

0.479

High

438663

SC160
Protein SCP160

1

20

High-throughput

0.479

High

441831

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.479

High

512052

RS4A
Small ribosomal subunit protein eS4A

1

1

High-throughput

0.479

High

514562

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.479

High

579167

HSC82
ATP-dependent molecular chaperone HSC82

1

12

High-throughput

0.479

High

645906

DBF2
Cell cycle protein kinase DBF2

1

12

High-throughput

0.479

High

674535

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

688995

RL16A
Large ribosomal subunit protein uL13A

1

4

High-throughput

0.479

High

694122

CDC15
Cell division control protein 15

1

10

High-throughput

0.479

High

721600

RENT1
ATP-dependent helicase NAM7

1

4

Small-scale

0.479

High

747792

SMY2
Protein SMY2

1

3

High-throughput

0.479

High

763819

RS27A
Small ribosomal subunit protein eS27A

1

4

High-throughput

0.479

High

763835

MOB1
DBF2 kinase activator protein MOB1

1

1

High-throughput

0.479

High

763848

XRN2
5'-3' exoribonuclease 2

1

5

High-throughput

0.479

High

763856

TSR1
Ribosome biogenesis protein TSR1

1

3

High-throughput

0.479

High

763857

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.479

High

763863

TMA46
Translation machinery-associated protein 46

1

3

High-throughput

0.479

High

763867

RL7B
Large ribosomal subunit protein uL30B

1

4

High-throughput

0.479

High

763868

SMC6
Structural maintenance of chromosomes protein 6

1

8

High-throughput

0.479

High

585250

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

3

High-throughput

0.470

High

763824

KPR2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.458

High

392530

HSP82
ATP-dependent molecular chaperone HSP82

1

12

High-throughput

0.445

High

453532

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.445

High

592162

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.445

High

670560

SIS1
Protein SIS1

1

9

High-throughput

0.445

High

675893

MAS5
Mitochondrial protein import protein MAS5

1

10

High-throughput

0.445

High

726921

HS104
Heat shock protein 104

1

5

High-throughput

0.445

High

741314

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

752098

HSP78
Heat shock protein 78, mitochondrial

1

5

High-throughput

0.445

High

763832

PFD2
Prefoldin subunit 2

1

2

High-throughput

0.445

High

763833

SSB2
Ribosome-associated molecular chaperone SSB2

1

14

High-throughput

0.445

High

763839

TCPQ
T-complex protein 1 subunit theta

1

3

High-throughput

0.445

High

383621

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.437

High

410049

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.437

High

433561

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.437

High

435544

RS9B
Small ribosomal subunit protein uS4B

1

6

High-throughput

0.437

High

454979

RS19A
Small ribosomal subunit protein eS19A

1

7

High-throughput

0.437

High

455392

RS19B
Small ribosomal subunit protein eS19B

1

7

High-throughput

0.437

High

502966

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.437

High

512363

RS6A
Small ribosomal subunit protein eS6A

1

5

High-throughput

0.437

High

512927

RS8A
Small ribosomal subunit protein eS8A

1

4

High-throughput

0.437

High

513976

RL18B
Large ribosomal subunit protein eL18B

1

2

High-throughput

0.437

High

515072

RL19B
Large ribosomal subunit protein eL19

1

2

High-throughput

0.437

High

689370

RS7A
Small ribosomal subunit protein eS7A

1

4

High-throughput

0.437

High

706733

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

739590

SPT16
FACT complex subunit SPT16

1

2

Small-scale

0.437

High

747281

RSSA1
Small ribosomal subunit protein uS2A

1

3

High-throughput

0.437

High

753289

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.437

High

763828

TEM1
Protein TEM1

1

1

High-throughput

0.437

High

763830

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

763834

RL13B
Large ribosomal subunit protein eL13B

1

3

High-throughput

0.437

High

763840

RS7B
Small ribosomal subunit protein eS7B

1

4

High-throughput

0.437

High

763845

RRP46
Exosome complex component RRP46

1

17

High-throughput

0.437

High

763847

RL6A
Large ribosomal subunit protein eL6A

1

2

High-throughput

0.437

High

763852

SCC2
Sister chromatid cohesion protein 2

1

4

High-throughput

0.437

High

763853

PDS5
Sister chromatid cohesion protein PDS5

1

1

High-throughput

0.437

High

763858

RRP44
Exosome complex exonuclease DIS3

1

8

High-throughput

0.437

High

763862

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

763864

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.437

High

365010

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.426

High

386662

TBB
Tubulin beta chain

1

0

High-throughput

0.426

High

763854

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.426

High

763836

DJP1
DnaJ-like protein 1

1

9

High-throughput

0.407

High

763837

SPR3
Sporulation-regulated protein 3

1

0

High-throughput

0.251

Low

763838

NUP85
Nucleoporin NUP85

1

0

High-throughput

0.249

Low

763822

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.232

Low

763865

NSL1
Kinetochore-associated protein NSL1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025