HitPredict

Interactor 1: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Interactor 2: LST8 (Q9BVC4)
Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8)
Gene: MLST8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 326
+	Hs
		903467 TCPH_HUMAN (1-543): 0: 647: 100.00		WDR5_HUMAN (79-326): 3.77e-74: 233: 20.57
+	Hs
		826860 TCPG_HUMAN (1-541): 0: 577: 31.09		LST8_HUMAN (1-326): 1.45e-95: 287: 100.00
+	Hs
		1240450 TCPH_HUMAN (1-543): 0: 647: 100.00		POC1A_HUMAN (122-325): 1.44e-56: 190: 20.10
+	Hs
		826601 TCPG_HUMAN (1-541): 0: 577: 31.09		WDR5_HUMAN (79-326): 3.77e-74: 233: 20.57
+	Hs
		821152 TCPE_HUMAN (3-527): 0: 557: 29.59		WDR5_HUMAN (79-326): 3.77e-74: 233: 20.57
+	Hs
		826772 TCPG_HUMAN (1-541): 0: 577: 31.09		POC1A_HUMAN (122-325): 1.44e-56: 190: 20.10
+	Hs
		197078 TCPH_HUMAN (1-543): 0: 647: 100.00		PRP4_HUMAN (157-324): 2.36e-27: 113: 18.75
+	Hs
		1202777 TCPH_HUMAN (1-543): 0: 647: 100.00		WDR5B_HUMAN (200-322): 9.78e-28: 112: 26.83
+	Hs
		826784 TCPG_HUMAN (1-541): 0: 577: 31.09		POC1B_HUMAN (119-325): 4.27e-53: 182: 18.36
+	Hs
		821316 TCPE_HUMAN (3-527): 0: 557: 29.59		POC1A_HUMAN (122-325): 1.44e-56: 190: 20.10
+	Hs
		821326 TCPE_HUMAN (3-527): 0: 557: 29.59		POC1B_HUMAN (119-325): 4.27e-53: 182: 18.36
+	Sc
		783336 TCPH_YEAST (2-542): 0: 587: 62.45		LST8_YEAST (2-229): 2.46e-42: 150: 14.47
+	At
		1339925 TCPH_ARATH (1-529): 0: 583: 67.67		LST81_ARATH (99-322): 1.96e-40: 145: 12.45
+	Hs
		1306704 TCPH_HUMAN (1-543): 0: 647: 100.00		NLE1_HUMAN (260-324): 3.72e-16: 80.8: 20.00
+	Dm
		1367313 Q9VHL2_DROME (2-527): 0: 592: 76.24		LST8_DROME (1-178): 1.15e-35: 132: 18.48
+	Hs
		1306654 TCPH_HUMAN (1-543): 0: 647: 100.00		KTNB1_HUMAN (14-199): 7.11e-09: 58.9: 22.46
+	Hs
		196973 TCPG_HUMAN (1-541): 0: 577: 31.09		PRP4_HUMAN (157-324): 2.36e-27: 113: 18.75
+	Hs
		826748 TCPG_HUMAN (1-541): 0: 577: 31.09		WDR5B_HUMAN (200-322): 9.78e-28: 112: 26.83
+	Hs
		196971 TCPE_HUMAN (3-527): 0: 557: 29.59		PRP4_HUMAN (157-324): 2.36e-27: 113: 18.75
+	Hs
		792942 TCPG_HUMAN (1-541): 0: 577: 31.09		LIS1_HUMAN (259-324): 8.45e-12: 67.3: 24.24