HitPredict

Interactor 1: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Interactor 2: DTL (Q9NZJ0)
Denticleless protein homolog (DDB1- and CUL4-associated factor 2) (Lethal(2) denticleless protein homolog) (Retinoic acid-regulated nuclear matrix-associated protein)
Gene: DTL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 730
+	Hs
		826921 TCPG_HUMAN (1-541): 0: 577: 31.09		DTL_HUMAN (1-730): 8.94e-163: 489: 100.00
+	Sp
		953439 TCPH_SCHPO (3-542): 0: 609: 64.97		CDT2_SCHPO (52-391): 1.12e-72: 246: 24.66
+	Hs
		1202777 TCPH_HUMAN (1-543): 0: 647: 100.00		WDR5B_HUMAN (190-502): 2.83e-55: 194: 16.51
+	Hs
		903467 TCPH_HUMAN (1-543): 0: 647: 100.00		WDR5_HUMAN (11-243): 2.2e-54: 192: 13.95
+	Hs
		826784 TCPG_HUMAN (1-541): 0: 577: 31.09		POC1B_HUMAN (14-281): 7.79e-64: 222: 14.72
+	Hs
		826807 TCPG_HUMAN (1-541): 0: 577: 31.09		FBXW7_HUMAN (175-521): 4.51e-54: 200: 12.16
+	Hs
		826748 TCPG_HUMAN (1-541): 0: 577: 31.09		WDR5B_HUMAN (190-502): 2.83e-55: 194: 16.51
+	Hs
		826601 TCPG_HUMAN (1-541): 0: 577: 31.09		WDR5_HUMAN (11-243): 2.2e-54: 192: 13.95
+	Hs
		1240450 TCPH_HUMAN (1-543): 0: 647: 100.00		POC1A_HUMAN (256-429): 6.94e-28: 118: 24.71
+	Hs
		821152 TCPE_HUMAN (3-527): 0: 557: 29.59		WDR5_HUMAN (11-243): 2.2e-54: 192: 13.95
+	Hs
		236248 TCPH_HUMAN (1-543): 0: 647: 100.00		PRP17_HUMAN (16-169): 9.6e-20: 95.8: 16.97
+	Hs
		1306704 TCPH_HUMAN (1-543): 0: 647: 100.00		NLE1_HUMAN (343-590): 4e-15: 80.5: 10.97
+	Hs
		1306645 TCPH_HUMAN (1-543): 0: 647: 100.00		TBL1Y_HUMAN (345-587): 1.16e-12: 73.2: 12.95
+	Hs
		792942 TCPG_HUMAN (1-541): 0: 577: 31.09		LIS1_HUMAN (260-499): 2.94e-36: 143: 15.23
+	Hs
		826772 TCPG_HUMAN (1-541): 0: 577: 31.09		POC1A_HUMAN (256-429): 6.94e-28: 118: 24.71
+	Sp
		953440 TCPH_SCHPO (3-542): 0: 609: 64.97		YN55_SCHPO (142-393): 1.21e-12: 71.1: 9.93
+	Hs
		821316 TCPE_HUMAN (3-527): 0: 557: 29.59		POC1A_HUMAN (256-429): 6.94e-28: 118: 24.71
+	Sc
		783336 TCPH_YEAST (2-542): 0: 587: 62.45		LST8_YEAST (107-400): 1.27e-15: 80.1: 26.25
+	Hs
		826848 TCPG_HUMAN (1-541): 0: 577: 31.09		TBL1Y_HUMAN (345-587): 1.16e-12: 73.2: 12.95
+	Sp
		251319 TCPG_SCHPO (2-525): 0: 560: 31.77		YN55_SCHPO (142-393): 1.21e-12: 71.1: 9.93