Protein: IMD
Protein immune deficiency

Gene: IMD
Organism: Drosophila melanogaster
Interactions: 120
UniProt ID: Q7K4Z4

Gene Ontology (top 5):
GO:0002230 - positive regulation of defense response to virus by host
GO:0002803 - positive regulation of antibacterial peptide production
GO:0005829 - cytosol
GO:0006955 - immune response
GO:0006959 - humoral immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1180281

FADD
Fas-associated death domain protein

6

0

Small-scale

0.890

High

1180264

IMD
Protein immune deficiency

1

0

Small-scale

0.674

High

1180278

PGPLC
Peptidoglycan-recognition protein LC

3

1

Small-scale

0.640

High

1180323

Q9W2E6
Poor Imd response upon knock-in, isoform A

3

0

Small-scale

0.613

High

186200

GBLP
Small ribosomal subunit protein RACK1

2

0

High-throughput

0.575

High

525356

EF2
Eukaryotic translation elongation factor 2

2

0

High-throughput

0.575

High

1180272

CASP8
Caspase-8

2

0

Small-scale

0.569

High

1097089

DIAP2
Death-associated inhibitor of apoptosis 2

2

0

Small-scale

0.559

High

53050

A1Z893
DI01187p

1

2

High-throughput

0.481

High

1180284

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

Small-scale

0.480

High

186116

PRS8
26S proteasome regulatory subunit 8

1

1

Small-scale

0.479

High

1180265

Q7KMQ0
26S proteasome regulatory subunit 7

1

1

High-throughput

0.479

High

1180283

PRDX2
Peroxiredoxin 2

1

2

High-throughput

0.479

High

1180314

PGPLE
Peptidoglycan-recognition protein LE

1

1

Small-scale

0.479

High

1180270

Q8I0N3
RE31819p

1

1

High-throughput

0.464

High

1180282

Q9V3G9
AT18705p

1

1

High-throughput

0.464

High

1180312

Q9VW23
Male sterile

1

1

High-throughput

0.464

High

116324

M9PI17
Aldo-keto reductase 1B, isoform D

1

0

High-throughput

0.458

High

185977

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.458

High

387949

CYC1
Cytochrome c-1

1

0

High-throughput

0.458

High

505067

HSP7D
Heat shock 70 kDa protein cognate 4

1

0

High-throughput

0.458

High

593949

NCD
Protein claret segregational

1

0

High-throughput

0.458

High

799751

CADF
Cofilin/actin-depolymerizing factor homolog

1

0

High-throughput

0.458

High

878807

FAF
Probable ubiquitin carboxyl-terminal hydrolase FAF

1

0

Small-scale

0.458

High

902190

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.458

High

1178488

Q7K012
Brahma associated protein 55kD

1

0

High-throughput

0.458

High

1180276

CATL
Cathepsin L

1

0

High-throughput

0.458

High

1180277

BCL9
Protein BCL9 homolog

1

0

High-throughput

0.458

High

1180279

JUPIT
Microtubule-associated protein Jupiter

1

0

High-throughput

0.458

High

1180294

VRET
Protein vreteno

1

0

High-throughput

0.458

High

1180300

Q9VHL2
T-complex protein 1 subunit eta

1

0

High-throughput

0.458

High

1180301

SMD2
Probable small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.458

High

1180303

SOYB
Putative ATP-dependent RNA helicase SoYb

1

0

High-throughput

0.458

High

1180309

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

Small-scale

0.458

High

1180310

FRL
Formin-like protein

1

0

High-throughput

0.458

High

1180330

RHGF
Rho GTPase-activating protein Graf

1

0

High-throughput

0.458

High

53044

A1Z892
LD11278p

1

2

High-throughput

0.457

High

1180266

Q7KTD2
SR family splicing factor SC35, isoform A

1

1

High-throughput

0.439

High

1180292

Q9VBE0
TweedleB

1

1

High-throughput

0.439

High

114147

HAKAI
E3 ubiquitin-protein ligase Hakai

1

0

High-throughput

0.438

High

52431

A1Z7K2
FI03455p

1

1

High-throughput

0.437

High

137752

CH60A
Heat shock protein 60A

1

1

High-throughput

0.437

High

415598

TBA1
Tubulin alpha-1 chain

1

2

High-throughput

0.437

High

415632

TBA2
Tubulin alpha-2 chain

1

2

High-throughput

0.437

High

415652

TBA3
Tubulin alpha-3 chain

1

2

High-throughput

0.437

High

669810

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.437

High

669846

HSP7E
Heat shock 70 kDa protein cognate 5

1

2

High-throughput

0.437

High

803313

RL7A
Large ribosomal subunit protein eL8

1

1

High-throughput

0.437

High

820634

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.437

High

1179607

Q7K3J0
T-complex protein 1 subunit theta

1

1

High-throughput

0.437

High

1180269

LIG
Protein lingerer

1

1

High-throughput

0.437

High

1180271

SLE
Protein slender lobes

1

1

High-throughput

0.437

High

1180280

NH2L1
NHP2-like protein 1 homolog

1

1

High-throughput

0.437

High

1180295

ATD3A
ATPase family AAA domain-containing protein 3A homolog

1

1

High-throughput

0.437

High

1180297

SLEL
Slender lobes-like protein

1

1

High-throughput

0.437

High

1180305

CH60C
60 kDa heat shock protein homolog 2, mitochondrial

1

1

High-throughput

0.437

High

1180327

Q9W392
T-complex protein 1 subunit beta

1

1

High-throughput

0.437

High

1180329

EAF3
NuA4 complex subunit EAF3 homolog

1

1

High-throughput

0.437

High

1180285

Q9V3T8
LD32469p

1

1

High-throughput

0.417

High

878834

RS20
Small ribosomal subunit protein uS10

2

0

High-throughput

0.313

High

137490

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

0

High-throughput

0.265

Low

854597

UBC84
Ubiquitin-conjugating enzyme E2-18 kDa

1

0

High-throughput

0.265

Low

1179174

Q7K264
LD16826p

1

0

High-throughput

0.265

Low

1180304

Q9VMC3
LD35051p

1

0

High-throughput

0.265

Low

1180311

ROGDI
Protein rogdi

1

0

High-throughput

0.265

Low

1180317

Q9W0C3
GH11843p

1

0

High-throughput

0.265

Low

1180328

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.265

Low

55808

A1ZB77
Uncharacterized protein, isoform J

1

0

High-throughput

0.249

Low

114810

M9PD90
Discs large 5, isoform D

1

0

High-throughput

0.249

Low

220649

CTBP
C-terminal-binding protein

1

0

High-throughput

0.249

Low

220746

O46048
EG:133E12.4 protein

1

0

High-throughput

0.249

Low

547883

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.249

Low

567391

CATA
Catalase

1

0

High-throughput

0.249

Low

611080

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

1

0

High-throughput

0.249

Low

613182

MA205
205 kDa microtubule-associated protein

1

0

High-throughput

0.249

Low

723135

ATPA
ATP synthase subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

836181

TAF6
Transcription initiation factor TFIID subunit 6

1

0

High-throughput

0.249

Low

842213

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.249

Low

948951

STIM
Stromal interaction molecule homolog

1

0

High-throughput

0.249

Low

954846

MIC60
MICOS complex subunit Mic60

1

0

High-throughput

0.249

Low

987872

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

1001891

Q0KI85
Sidestep VI, isoform B

1

0

High-throughput

0.249

Low

1097301

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.249

Low

1097928

CP190
Centrosome-associated zinc finger protein Cp190

1

0

High-throughput

0.249

Low

1098146

TBB1
Tubulin beta-1 chain

1

0

High-throughput

0.249

Low

1099439

ADT
ADP,ATP carrier protein

1

0

High-throughput

0.249

Low

1176374

Q76NQ0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

1180008

DGT5
Augmin complex subunit dgt5

1

0

High-throughput

0.249

Low

1180267

Q7KTV5
Nopp140, isoform B

1

0

High-throughput

0.249

Low

1180268

Q86BM5
A kinase anchor protein 200, isoform D

1

0

High-throughput

0.249

Low

1180273

LVA
Protein lava lamp

1

0

High-throughput

0.249

Low

1180274

Q8SYU0
Coiled-coil domain-containing protein 43

1

0

High-throughput

0.249

Low

1180275

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

0

High-throughput

0.249

Low

1180286

Q9V406
Activator protein 4

1

0

High-throughput

0.249

Low

1180287

PDIA6
Protein disulfide-isomerase A6 homolog

1

0

High-throughput

0.249

Low

1180288

HCF
Host cell factor

1

0

High-throughput

0.249

Low

1180289

ANLN
Anillin

1

0

High-throughput

0.249

Low

1180290

Q9VA35
CIN85 and CD2AP related, isoform A

1

0

High-throughput

0.249

Low

1180291

S39AD
Zinc transporter ZIP13 homolog

1

0

High-throughput

0.249

Low

1180293

Q9VBU9
40S ribosomal protein S27

1

0

High-throughput

0.249

Low

1180296

MBDR2
Protein MBD-R2

1

0

High-throughput

0.249

Low

1180298

RUVB1
RuvB-like helicase 1

1

0

High-throughput

0.249

Low

1180299

Q9VHH8
Beag

1

0

High-throughput

0.249

Low

1180302

Q9VJD1
Glucosidase 2 subunit beta

1

0

High-throughput

0.249

Low

1180306

Q9VP57
LD15904p

1

0

High-throughput

0.249

Low

1180307

Q9VPU7
Arouser, isoform C

1

0

High-throughput

0.249

Low

1180308

Q9VRL8
Blanks

1

0

High-throughput

0.249

Low

1180313

Q9VWP5
Hat-trick, isoform D

1

0

High-throughput

0.249

Low

1180315

Q9VXQ5
T-complex protein 1 subunit zeta

1

0

High-throughput

0.249

Low

1180316

Q9VZF2
LD05244p

1

0

High-throughput

0.249

Low

1180318

Q9W1B9
Large ribosomal subunit protein uL11

1

0

High-throughput

0.249

Low

1180319

Q9W1H5
Decapping protein 1, isoform A

1

0

High-throughput

0.249

Low

1180320

Q9W1I8
LD03592p

1

0

High-throughput

0.249

Low

1180321

NU214
Nuclear pore complex protein Nup214

1

0

High-throughput

0.249

Low

1180322

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.249

Low

1180324

Q9W2I4
FI01566p

1

0

High-throughput

0.249

Low

1180326

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.249

Low

1180331

X2JLM6
Ubiquitin carboxyl-terminal hydrolase

1

0

Small-scale

0.249

Low

1180325

Q9W2L2
LD27118p

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024