HitPredict

Interactor 1: SH3G1 (Q99961)
Endophilin-A2 (EEN fusion partner of MLL) (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1)
Gene: SH3GL1

Interactor 2: SH3G3 (Q99963)
Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)
Gene: SH3GL3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 16169070, 35271311, 21900206, 16115810, 26186194, 28514442, 33961781
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains BAR~BAR, SH3_1~SH3_1
Common GO terms GO:0005737 - cytoplasm
GO:0007165 - signal transduction
GO:0007417 - central nervous system development
GO:0008289 - lipid binding
GO:0016191 - synaptic vesicle uncoating
and 3 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 368
Hs

1 347
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024