Protein: SEM4C
Semaphorin-4C

Gene: SEM4C, SEMA4C
Organism: Homo sapiens
Interactions: 157
UniProt ID: Q9C0C4

Gene Ontology (top 5):
GO:0001755 - neural crest cell migration
GO:0001843 - neural tube closure
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0007411 - axon guidance

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

165243

PLXB2
Plexin-B2

1

20

High-throughput

0.691

High

1318972

SEM4A
Semaphorin-4A

1

15

High-throughput

0.691

High

1071383

K1H1
Keratin, type I cuticular Ha1

3

3

High-throughput

0.675

High

519423

FCERA
High affinity immunoglobulin epsilon receptor subunit alpha

1

0

High-throughput

0.656

High

348909

RASN
GTPase NRas

3

10

High-throughput

0.640

High

350524

RASK
GTPase KRas

3

10

High-throughput

0.640

High

1189437

NT2NA
Notch homolog 2 N-terminal-like protein A

2

9

High-throughput

0.633

High

280714

KRT34
Keratin, type I cuticular Ha4

2

3

High-throughput

0.606

High

702406

TNFL8
Tumor necrosis factor ligand superfamily member 8

2

0

High-throughput

0.602

High

592002

RAB4A
Ras-related protein Rab-4A

2

2

High-throughput

0.584

High

942378

DLG4
Disks large homolog 4

1

7

Small-scale

0.573

High

370388

ESR1
Estrogen receptor

2

4

High-throughput

0.571

High

158230

GIPC1
PDZ domain-containing protein GIPC1

2

5

High-throughput

0.558

High

67336

CRTP1
Cysteine-rich tail protein 1

2

1

High-throughput

0.553

High

253180

HSF2B
Heat shock factor 2-binding protein

2

1

High-throughput

0.553

High

445115

K1C16
Keratin, type I cytoskeletal 16

2

3

High-throughput

0.553

High

1189649

K1C27
Keratin, type I cytoskeletal 27

2

2

High-throughput

0.553

High

1236702

USBP1
Harmonin-binding protein USHBP1

2

1

High-throughput

0.553

High

1318989

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

1

High-throughput

0.553

High

119782

ARVC
Splicing regulator ARVCF

1

1

High-throughput

0.536

High

354890

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

12

High-throughput

0.536

High

449349

LEG1
Galectin-1

1

1

High-throughput

0.536

High

514473

PSPC
Surfactant protein C

1

3

High-throughput

0.536

High

598522

NF1
Neurofibromin

1

1

High-throughput

0.536

High

768512

TYRP2
L-dopachrome tautomerase

1

1

High-throughput

0.536

High

776812

STAT3
Signal transducer and activator of transcription 3

1

1

High-throughput

0.536

High

842025

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

1

High-throughput

0.536

High

980123

ATP7A
Copper-transporting ATPase 1

1

1

High-throughput

0.536

High

1056243

I13R2
Interleukin-13 receptor subunit alpha-2

1

6

High-throughput

0.536

High

1109765

CC50B
Cell cycle control protein 50B

1

2

High-throughput

0.536

High

1169435

NBEL2
Neurobeachin-like protein 2

1

1

High-throughput

0.536

High

1241736

DYHC2
Cytoplasmic dynein 2 heavy chain 1

1

8

High-throughput

0.536

High

1271058

SYMPK
Symplekin

1

1

High-throughput

0.536

High

1318991

PCDB3
Protocadherin beta-3

1

3

High-throughput

0.536

High

914341

RB11A
Ras-related protein Rab-11A

2

2

High-throughput

0.533

High

1149334

K1C40
Keratin, type I cytoskeletal 40

1

3

High-throughput

0.523

High

281873

WFS1
Wolframin

1

1

High-throughput

0.515

High

484709

NT2NC
Notch homolog 2 N-terminal-like protein C

1

9

High-throughput

0.515

High

131959

UPK2
Uroplakin-2

1

0

High-throughput

0.513

High

245409

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.513

High

835108

TSC2
Tuberin

1

0

High-throughput

0.513

High

1047807

CKAP5
Cytoskeleton-associated protein 5

1

0

High-throughput

0.513

High

1244363

FLCN
Folliculin

1

0

High-throughput

0.513

High

1251327

EXOC6
Exocyst complex component 6

1

0

High-throughput

0.513

High

1253534

CIP2A
Protein CIP2A

1

0

High-throughput

0.513

High

1318987

EXOC7
Exocyst complex component 7

1

0

High-throughput

0.513

High

240174

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

1

High-throughput

0.500

High

1047253

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

3

High-throughput

0.500

High

1317435

TRI54
Tripartite motif-containing protein 54

1

4

High-throughput

0.494

High

163642

BTAF1
TATA-binding protein-associated factor 172

1

7

High-throughput

0.489

High

236975

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

1

High-throughput

0.489

High

256779

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

4

High-throughput

0.489

High

787558

MTOR
Serine/threonine-protein kinase mTOR

1

9

High-throughput

0.489

High

819429

GSH0
Glutamate--cysteine ligase regulatory subunit

1

3

High-throughput

0.489

High

1038169

ATR
Serine/threonine-protein kinase ATR

1

11

High-throughput

0.489

High

1066651

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.489

High

1146077

TBC9B
TBC1 domain family member 9B

1

1

High-throughput

0.489

High

1164541

SARM1
NAD(+) hydrolase SARM1

1

1

High-throughput

0.489

High

1232570

STAG2
Cohesin subunit SA-2

1

2

High-throughput

0.489

High

1260131

TGFA1
Transforming growth factor-beta receptor-associated protein 1

1

1

High-throughput

0.489

High

1318678

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

4

High-throughput

0.489

High

1318978

HELLS
Lymphoid-specific helicase

1

4

High-throughput

0.489

High

1318982

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

1

High-throughput

0.489

High

1318984

FBX2
F-box only protein 2

1

7

High-throughput

0.489

High

1318988

PLAP
Phospholipase A-2-activating protein

1

2

High-throughput

0.489

High

1318992

TNPO3
Transportin-3

1

1

High-throughput

0.489

High

1318996

NEMO
NF-kappa-B essential modulator

1

2

High-throughput

0.489

High

1077287

DLG2
Disks large homolog 2

1

7

Small-scale

0.481

High

1271025

DLG3
Disks large homolog 3

1

7

Small-scale

0.481

High

178761

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

205948

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.479

High

318219

DIRA3
GTP-binding protein Di-Ras3

1

2

High-throughput

0.479

High

349625

RASH
GTPase HRas

1

9

High-throughput

0.479

High

433990

LYN
Tyrosine-protein kinase Lyn

1

3

High-throughput

0.479

High

567254

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

591674

RAB3B
Ras-related protein Rab-3B

1

2

High-throughput

0.479

High

592478

RAB5A
Ras-related protein Rab-5A

1

3

High-throughput

0.479

High

844719

RAB5C
Ras-related protein Rab-5C

1

3

High-throughput

0.479

High

845224

RAB7A
Ras-related protein Rab-7a

1

4

High-throughput

0.479

High

845715

RAB9A
Ras-related protein Rab-9A

1

4

High-throughput

0.479

High

872092

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

2

High-throughput

0.479

High

884586

RAB25
Ras-related protein Rab-25

1

2

High-throughput

0.479

High

915952

RHOB
Rho-related GTP-binding protein RhoB

1

5

High-throughput

0.479

High

1017781

STX4
Syntaxin-4

1

3

High-throughput

0.479

High

1070385

RAB35
Ras-related protein Rab-35

1

2

High-throughput

0.479

High

1230359

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.479

High

1263270

5HT3C
5-hydroxytryptamine receptor 3C

1

2

High-throughput

0.479

High

1285644

ARL8A
ADP-ribosylation factor-like protein 8A

1

1

High-throughput

0.479

High

1318980

CC50A
Cell cycle control protein 50A

1

2

High-throughput

0.479

High

1318986

AT1B4
Protein ATP1B4

1

2

High-throughput

0.479

High

1257219

GIPC2
PDZ domain-containing protein GIPC2

1

5

High-throughput

0.470

High

218065

PEX1
Peroxisomal ATPase PEX1

1

1

High-throughput

0.470

High

352700

TNFA
Tumor necrosis factor

1

0

High-throughput

0.458

High

430329

PROF1
Profilin-1

1

0

High-throughput

0.458

High

913095

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

1084167

OCLN
Occludin

1

0

High-throughput

0.458

High

1152084

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1165934

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1254992

MCLN3
Mucolipin-3

1

0

High-throughput

0.458

High

1318985

MYO6
Unconventional myosin-VI

1

0

High-throughput

0.458

High

497567

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

625

NBPFJ
Neuroblastoma breakpoint family member 19

1

3

High-throughput

0.439

High

1146815

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

1203838

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

1240760

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.437

High

1269550

ESR2
Estrogen receptor beta

1

4

High-throughput

0.437

High

1283053

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

1303547

SEC62
Translocation protein SEC62

1

1

High-throughput

0.437

High

1318976

FBX6
F-box only protein 6

1

7

High-throughput

0.437

High

1242295

PNMA1
Paraneoplastic antigen Ma1

3

0

High-throughput

0.352

High

1318975

SACA1
Sperm acrosome membrane-associated protein 1

3

0

High-throughput

0.347

High

1299469

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.299

High

130102

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.279

Low

155635

TNPO2
Transportin-2

1

0

High-throughput

0.279

Low

167277

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

0

High-throughput

0.279

Low

167612

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

0

High-throughput

0.279

Low

311618

SMC2
Structural maintenance of chromosomes protein 2

1

0

High-throughput

0.279

Low

314493

APOM
Apolipoprotein M

1

0

High-throughput

0.279

Low

538021

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.279

Low

632894

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.279

Low

654743

CALX
Calnexin

1

0

High-throughput

0.279

Low

777258

PEX19
Peroxisomal biogenesis factor 19

1

0

High-throughput

0.279

Low

789340

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.279

Low

856239

HXK2
Hexokinase-2

1

0

High-throughput

0.279

Low

1048960

UBE4A
Ubiquitin conjugation factor E4 A

1

0

High-throughput

0.279

Low

1058876

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

High-throughput

0.279

Low

1132852

DPS1
All trans-polyprenyl-diphosphate synthase PDSS1

1

0

High-throughput

0.279

Low

1157529

MZT2B
Mitotic-spindle organizing protein 2B

1

0

High-throughput

0.279

Low

1161967

FIGL1
Fidgetin-like protein 1

1

0

High-throughput

0.279

Low

1190562

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

1191073

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.279

Low

1205279

DAAF5
Dynein axonemal assembly factor 5

1

0

High-throughput

0.279

Low

1236208

ZFN2A
AN1-type zinc finger protein 2A

1

0

High-throughput

0.279

Low

1242355

LRN4L
LRRN4 C-terminal-like protein

1

0

High-throughput

0.279

Low

1282824

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.279

Low

1284732

TTC28
Tetratricopeptide repeat protein 28

1

0

High-throughput

0.279

Low

1287570

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.279

Low

1295262

ELMO2
Engulfment and cell motility protein 2

1

0

High-throughput

0.279

Low

1312982

MSTO1
Protein misato homolog 1

1

0

High-throughput

0.279

Low

1318968

XPO4
Exportin-4

1

0

High-throughput

0.279

Low

1318969

BTBD1
BTB/POZ domain-containing protein 1

1

0

High-throughput

0.279

Low

1318970

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

0

High-throughput

0.279

Low

1318974

COG4
Conserved oligomeric Golgi complex subunit 4

1

0

High-throughput

0.279

Low

1318977

F1142
Protein FAM114A2

1

0

High-throughput

0.279

Low

1318983

KLH42
Kelch-like protein 42

1

0

High-throughput

0.279

Low

1318990

NUB1
NEDD8 ultimate buster 1

1

0

High-throughput

0.279

Low

1318993

SNX5
Sorting nexin-5

1

0

High-throughput

0.279

Low

1318994

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

0

High-throughput

0.279

Low

1318995

TX264
Testis-expressed protein 264

1

0

High-throughput

0.279

Low

1109356

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.268

Low

890399

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.249

Low

1119619

MIDN
Midnolin

1

0

High-throughput

0.249

Low

1296896

SNX27
Sorting nexin-27

1

0

High-throughput

0.249

Low

1318971

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low

1318973

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.249

Low

1318979

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1318981

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024