Interactor 1: PLD3 (Q8IV08)
5'-3' exonuclease PLD3 (EC 3.1.16.1) ((S,S)-bis(monoacylglycero)phosphate synthase PLD3) (EC 3.1.4.-) (HindIII K4L homolog) (Hu-K4) (Phospholipase D3)
Gene: PLD3
Interactor 2: PLD4 (Q96BZ4)
5'-3' exonuclease PLD4 (EC 3.1.16.1) ((S,S)-bis(monoacylglycero)phosphate synthase PLD4) (EC 3.1.4.-) (Phospholipase D family member 4) (Phospholipase D4)
Gene: PLD4
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35007762 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PLDc_3~PLDc_3 |
| Common GO terms | GO:0005789 - endoplasmic reticulum membrane GO:0006629 - lipid metabolic process GO:0006954 - inflammatory response GO:0045145 - single-stranded DNA 5'-3' DNA exonuclease activity GO:1900015 - regulation of cytokine production involved in inflammatory response |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
