Protein: PLD4
5'-3' exonuclease PLD4 (EC 3.1.16.1) ((S,S)-bis(monoacylglycero)phosphate synthase PLD4) (EC 3.1.4.-) (Phospholipase D family member 4) (Phospholipase D4)

Gene: PLD4
Organism: Homo sapiens
Interactions: 81
UniProt ID: Q96BZ4

Gene Ontology (top 5):
GO:0002244 - hematopoietic progenitor cell differentiation
GO:0005634 - nucleus
GO:0005764 - lysosome
GO:0005769 - early endosome
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1308184

PLD3
5'-3' exonuclease PLD3

1

2

High-throughput

0.618

High

1385224

PLD4
5'-3' exonuclease PLD4

1

2

High-throughput

0.618

High

390720

TFR1
Transferrin receptor protein 1

1

1

High-throughput

0.479

High

418342

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

431870

ITB1
Integrin beta-1

1

1

High-throughput

0.479

High

448059

ITAV
Integrin alpha-V

1

3

High-throughput

0.479

High

452361

PDIA1
Protein disulfide-isomerase

1

8

High-throughput

0.479

High

535390

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.479

High

566793

PDIA4
Protein disulfide-isomerase A4

1

8

High-throughput

0.479

High

573612

ENPL
Endoplasmin

1

1

High-throughput

0.479

High

716214

ERP29
Endoplasmic reticulum resident protein 29

1

8

High-throughput

0.479

High

717569

PDIA3
Protein disulfide-isomerase A3

1

9

High-throughput

0.479

High

863533

STT3A
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

1

1

High-throughput

0.479

High

876717

HSP13
Heat shock 70 kDa protein 13

1

1

High-throughput

0.479

High

895629

SERPH
Serpin H1

1

2

High-throughput

0.479

High

999549

NOMO3
BOS complex subunit NOMO3

1

1

High-throughput

0.479

High

1098461

DNJC3
DnaJ homolog subfamily C member 3

1

8

High-throughput

0.479

High

1105537

OS9
Protein OS-9

1

3

High-throughput

0.479

High

1131347

GANAB
Neutral alpha-glucosidase AB

1

1

High-throughput

0.479

High

1142359

PDIA6
Protein disulfide-isomerase A6

1

9

High-throughput

0.479

High

1257536

TMTC3
Protein O-mannosyl-transferase TMTC3

1

5

High-throughput

0.479

High

1275388

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

1

High-throughput

0.479

High

1324381

ABD12
Lysophosphatidylserine lipase ABHD12

1

1

High-throughput

0.479

High

1330349

EMC1
ER membrane protein complex subunit 1

1

1

High-throughput

0.479

High

1349812

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

1

High-throughput

0.479

High

1364052

NICA
Nicastrin

1

1

High-throughput

0.479

High

1366357

GPI8
GPI-anchor transamidase

1

1

High-throughput

0.479

High

1385226

TMX3
Protein disulfide-isomerase TMX3

1

8

High-throughput

0.479

High

1385229

SDF2
Stromal cell-derived factor 2

1

1

High-throughput

0.479

High

1385232

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

1

High-throughput

0.479

High

1385233

SDF2L
Stromal cell-derived factor 2-like protein 1

1

1

High-throughput

0.479

High

1385235

ITM2C
Integral membrane protein 2C

1

1

High-throughput

0.479

High

1385236

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

1

High-throughput

0.479

High

1385238

SELN
Selenoprotein N

1

1

High-throughput

0.479

High

1385239

HACD3
Very-long-chain

1

1

High-throughput

0.479

High

1385241

HYOU1
Hypoxia up-regulated protein 1

1

1

High-throughput

0.479

High

280299

SC22B
Vesicle-trafficking protein SEC22b

1

0

High-throughput

0.458

High

402398

GBA1
Lysosomal acid glucosylceramidase

1

0

High-throughput

0.458

High

582353

ARSA
Arylsulfatase A

1

0

High-throughput

0.458

High

582394

B4GT1
Beta-1,4-galactosyltransferase 1

1

0

High-throughput

0.458

High

656218

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

High-throughput

0.458

High

869939

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

0

High-throughput

0.458

High

957993

RAB14
Ras-related protein Rab-14

1

0

High-throughput

0.458

High

1097022

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.458

High

1105862

TMED1
Transmembrane emp24 domain-containing protein 1

1

0

High-throughput

0.458

High

1116901

MOGS
Mannosyl-oligosaccharide glucosidase

1

0

High-throughput

0.458

High

1122644

MLEC
Malectin

1

0

High-throughput

0.458

High

1155252

VAS1
V-type proton ATPase subunit S1

1

0

High-throughput

0.458

High

1333436

XXLT1
Xyloside xylosyltransferase 1

1

0

High-throughput

0.458

High

1333563

SUMF2
Inactive C-alpha-formylglycine-generating enzyme 2

1

0

High-throughput

0.458

High

1350121

SPP
Signal peptide peptidase

1

0

High-throughput

0.458

High

1352918

PO210
Nuclear pore membrane glycoprotein 210

1

0

High-throughput

0.458

High

1381324

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.458

High

1383760

FKB10
Peptidyl-prolyl cis-trans isomerase FKBP10

1

0

High-throughput

0.458

High

1385227

H2A1H
Histone H2A type 1-H

1

0

High-throughput

0.458

High

1385228

PIGS
GPI-anchor transamidase component PIGS

1

0

High-throughput

0.458

High

1385231

CHID1
Chitinase domain-containing protein 1

1

0

High-throughput

0.458

High

1385237

ERAP1
Endoplasmic reticulum aminopeptidase 1

1

0

High-throughput

0.458

High

186437

TM9S1
Transmembrane 9 superfamily member 1

1

5

High-throughput

0.437

High

316548

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

2

High-throughput

0.437

High

467572

4F2
Amino acid transporter heavy chain SLC3A2

1

1

High-throughput

0.437

High

476012

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

1

High-throughput

0.437

High

1031838

LAT1
Large neutral amino acids transporter small subunit 1

1

1

High-throughput

0.437

High

1101767

PTK7
Inactive tyrosine-protein kinase 7

1

4

High-throughput

0.437

High

1124283

IF4A2
Eukaryotic initiation factor 4A-II

1

2

High-throughput

0.437

High

1253786

QSOX2
Sulfhydryl oxidase 2

1

10

High-throughput

0.437

High

1315943

CHSS2
Chondroitin sulfate synthase 2

1

2

High-throughput

0.437

High

1385225

ERLEC
Endoplasmic reticulum lectin 1

1

3

High-throughput

0.437

High

1385230

TM9S2
Transmembrane 9 superfamily member 2

1

5

High-throughput

0.437

High

1385234

TM9S3
Transmembrane 9 superfamily member 3

1

5

High-throughput

0.437

High

1385240

CHPF2
Chondroitin sulfate glucuronyltransferase

1

2

High-throughput

0.437

High

1227217

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.407

High

219346

B4GA1
Beta-1,4-glucuronyltransferase 1

1

0

High-throughput

0.249

Low

252539

SEP15
Selenoprotein F

1

0

High-throughput

0.249

Low

277033

ENTP6
Ectonucleoside triphosphate diphosphohydrolase 6

1

0

High-throughput

0.249

Low

942809

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.249

Low

1023007

FAM3A
Protein FAM3A

1

0

High-throughput

0.249

Low

1052168

COEA1
Collagen alpha-1(XIV) chain

1

0

High-throughput

0.249

Low

1248721

SBSN
Suprabasin

1

0

High-throughput

0.249

Low

1251504

CD109
CD109 antigen

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025