Interactor 1: VRK3 (Q8IV63)
Serine/threonine-protein kinase VRK3 (EC 2.7.11.22) (Vaccinia-related kinase 3)
Gene: VRK3
Interactor 2: TLR9 (Q9NR96)
Toll-like receptor 9 (CD antigen CD289)
Gene: TLR9
Species: Homo sapiens
Source: innatedb
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17353931 |
| Identification Methods | affinity technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_6~Pkinase, LRR_8~Pkinase |
| Common GO terms | GO:0005737 - cytoplasm GO:0070373 - negative regulation of ERK1 and ERK2 cascade |
| Homologous interactions | 1 |
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Last updated: 11Aug2025