Protein: SLIT2
Slit homolog 2 protein (Slit-2) [Cleaved into: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product]

Gene: SLIT2
Organism: Homo sapiens
Interactions: 65
UniProt ID: O94813

Gene Ontology (top 5):
GO:0001657 - ureteric bud development
GO:0001933 - negative regulation of protein phosphorylation
GO:0002042 - cell migration involved in sprouting angiogenesis
GO:0002689 - negative regulation of leukocyte chemotaxis
GO:0003180 - aortic valve morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

317595

PRG3
Proteoglycan 3

2

7

High-throughput

0.811

High

317537

SLIT2
Slit homolog 2 protein

1

19

Small-scale

0.692

High

317597

ROBO1
Roundabout homolog 1

1

15

Small-scale

0.692

High

317549

PGFRA
Platelet-derived growth factor receptor alpha

1

7

High-throughput

0.691

High

317563

NOTC2
Neurogenic locus notch homolog protein 2

1

17

High-throughput

0.691

High

317596

ST14
Suppressor of tumorigenicity 14 protein

1

11

High-throughput

0.691

High

185305

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

3

High-throughput

0.647

High

317559

DEF1
Neutrophil defensin 1

2

2

High-throughput

0.628

High

230607

PRIC3
Prickle planar cell polarity protein 3

1

8

High-throughput

0.618

High

188755

TMPS2
Transmembrane protease serine 2

1

13

High-throughput

0.618

High

317541

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.618

High

317556

KC1E
Casein kinase I isoform epsilon

1

2

High-throughput

0.618

High

317557

LUM
Lumican

1

19

High-throughput

0.618

High

317581

ROBO4
Roundabout homolog 4

1

20

Small-scale

0.618

High

317591

TMPS4
Transmembrane protease serine 4

1

13

High-throughput

0.618

High

317558

IMA5
Importin subunit alpha-5

2

2

High-throughput

0.601

High

317573

ANR12
Ankyrin repeat domain-containing protein 12

3

19

High-throughput

0.599

High

317553

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

2

Small-scale

0.561

High

317577

LRC47
Leucine-rich repeat-containing protein 47

1

20

High-throughput

0.553

High

317580

CLC4D
C-type lectin domain family 4 member D

1

2

High-throughput

0.553

High

317546

CCL3
C-C motif chemokine 3

1

4

High-throughput

0.536

High

317552

CALX
Calnexin

1

4

High-throughput

0.536

High

317565

TP53B
TP53-binding protein 1

1

2

High-throughput

0.536

High

317576

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

317583

ARRD3
Arrestin domain-containing protein 3

1

1

High-throughput

0.536

High

317586

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

2

High-throughput

0.536

High

317594

FBX2
F-box only protein 2

1

8

High-throughput

0.536

High

317542

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

317543

MSMB
Beta-microseminoprotein

1

0

High-throughput

0.513

High

317566

SG2A2
Mammaglobin-A

1

0

High-throughput

0.513

High

317544

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

6

High-throughput

0.501

High

317555

HXA1
Homeobox protein Hox-A1

1

7

High-throughput

0.494

High

317539

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.489

High

317545

GLI4
Zinc finger protein GLI4

1

16

High-throughput

0.489

High

317538

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

317548

ETS1
Protein C-ets-1

1

1

High-throughput

0.479

High

317550

BRD2
Bromodomain-containing protein 2

1

7

High-throughput

0.479

High

317551

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.479

High

317560

SC61B
Protein transport protein Sec61 subunit beta

1

3

High-throughput

0.479

High

317562

TF65
Transcription factor p65

1

3

High-throughput

0.479

High

317564

EXOS9
Exosome complex component RRP45

1

2

High-throughput

0.479

High

317567

CUL3
Cullin-3

1

8

High-throughput

0.479

High

317575

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

11

High-throughput

0.479

High

317587

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

317589

EXOS4
Exosome complex component RRP41

1

1

High-throughput

0.479

High

317590

BRD7
Bromodomain-containing protein 7

1

2

High-throughput

0.479

High

317592

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

5

High-throughput

0.479

High

317593

XPO7
Exportin-7

1

1

High-throughput

0.479

High

317547

IFM1
Interferon-induced transmembrane protein 1

1

0

High-throughput

0.458

High

317554

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

0

High-throughput

0.458

High

317561

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.458

High

317568

PTC1
Protein patched homolog 1

1

0

High-throughput

0.458

High

317569

EXOS2
Exosome complex component RRP4

1

0

High-throughput

0.458

High

317570

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

317584

RSRC1
Serine/Arginine-related protein 53

1

0

High-throughput

0.458

High

317582

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

7

High-throughput

0.457

High

317540

B3AT
Band 3 anion transport protein

1

3

High-throughput

0.445

High

317571

EXOS7
Exosome complex component RRP42

1

2

High-throughput

0.437

High

317574

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

317588

RN208
RING finger protein 208

1

3

Small-scale

0.437

High

317578

POC5
Centrosomal protein POC5

1

0

High-throughput

0.426

High

317585

MF14A
Hippocampus abundant transcript 1 protein

1

0

High-throughput

0.426

High

317572

Q6PG48
ANKRD12 protein

1

9

High-throughput

0.407

High

317579

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025