HitPredict

Interactor 1: ZFY21 (Q9BQ24)
Zinc finger FYVE domain-containing protein 21 (ZF21)
Gene: ZFYVE21

Interactor 2: TRIM1 (Q9UJV3)
Probable E3 ubiquitin-protein ligase MID2 (EC 2.3.2.27) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (RING-type E3 ubiquitin transferase MID2) (Tripartite motif-containing protein 1)
Gene: MID2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.523

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 234 Hs			1 735
+	Hs
		175716 ZFYV1_HUMAN (14-112): 4.42e-18: 84.4: 29.25		TRI18_HUMAN (21-717): 8.76e-175: 518: 72.60
+	Hs
		1172339 FYV1_HUMAN (2-170): 2.32e-38: 143: 26.88		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		1171447 FYCO1_HUMAN (3-173): 1.97e-35: 135: 21.64		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		1170581 ZFY16_HUMAN (2-202): 3.05e-35: 134: 24.38		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		1170759 WDFY3_HUMAN (3-115): 2.32e-33: 129: 24.78		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		1040934 MTMR3_HUMAN (5-123): 3.41e-32: 125: 27.73		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		160053 HGS_HUMAN (23-188): 3.11e-32: 125: 22.16		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		1171006 RUFY2_HUMAN (7-112): 9.83e-30: 118: 23.59		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		1171357 RUFY1_HUMAN (4-112): 8.06e-30: 118: 24.77		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		1172084 ANFY1_HUMAN (36-103): 7.64e-25: 104: 36.77		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		50876 HGS_HUMAN (23-188): 3.11e-32: 125: 22.16		FSD2_HUMAN (206-712): 2.04e-81: 276: 22.86
+	Hs
		537017 ZFY21_HUMAN (1-234): 4.05e-94: 277: 100.00		TRI27_HUMAN (16-340): 1.18e-23: 107: 14.15
+	Hs
		160179 HGS_HUMAN (23-188): 3.11e-32: 125: 22.16		TRI54_HUMAN (184-400): 2.63e-53: 190: 23.96
+	Hs
		1224704 WDFY3_HUMAN (3-115): 2.32e-33: 129: 24.78		TRI39_HUMAN (21-389): 6.9e-27: 117: 12.81
+	Hs
		3236 A0A0S2Z4Q4_HUMAN (23-173): 1.24e-33: 129: 24.34		TRI27_HUMAN (16-340): 1.18e-23: 107: 14.15
+	Hs
		159870 HGS_HUMAN (23-188): 3.11e-32: 125: 22.16		TRI27_HUMAN (16-340): 1.18e-23: 107: 14.15
+	Hs
		159914 HGS_HUMAN (23-188): 3.11e-32: 125: 22.16		TRI23_HUMAN (28-272): 6.41e-17: 86.7: 24.71
+	Hs
		1223390 PKHF2_HUMAN (28-119): 6.6e-25: 100: 29.41		TRI22_HUMAN (23-287): 2.15e-24: 109: 16.48
+	Hs
		734740 RUFY1_HUMAN (4-112): 8.06e-30: 118: 24.77		TRI23_HUMAN (28-272): 6.41e-17: 86.7: 24.71
+	Hs
		1049163 MTMR4_HUMAN (17-123): 1.31e-29: 118: 30.28		TRI14_HUMAN (192-413): 5.06e-11: 67.6: 19.30