Protein: SC65
Endoplasmic reticulum protein SC65 (Leprecan-like protein 4) (Nucleolar autoantigen No55) (Prolyl 3-hydroxylase family member 4) (Synaptonemal complex protein SC65)

Gene: SC65, P3H4
Organism: Homo sapiens
Interactions: 80
UniProt ID: Q92791

Gene Ontology (top 5):
GO:0000794 - condensed nuclear chromosome
GO:0000795 - synaptonemal complex
GO:0005730 - nucleolus
GO:0005783 - endoplasmic reticulum
GO:0007130 - synaptonemal complex assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1038920

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

2

3

High-throughput

0.628

High

1368429

C1QT2
Complement C1q tumor necrosis factor-related protein 2

3

20

High-throughput

0.609

High

326208

ALX3
Homeobox protein aristaless-like 3

2

3

High-throughput

0.574

High

1258458

CHSS3
Chondroitin sulfate synthase 3

2

1

High-throughput

0.574

High

1368441

COLQ
Acetylcholinesterase collagenic tail peptide

2

10

High-throughput

0.574

High

388732

C1QB
Complement C1q subcomponent subunit B

2

20

High-throughput

0.558

High

567938

PRG2
Bone marrow proteoglycan

2

5

High-throughput

0.558

High

647389

IDS
Iduronate 2-sulfatase

2

2

High-throughput

0.558

High

1368443

COL10
Collectin-10

2

12

High-throughput

0.558

High

73840

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

2

20

High-throughput

0.549

High

698973

CALX
Calnexin

1

2

High-throughput

0.536

High

1105530

OS9
Protein OS-9

1

1

High-throughput

0.536

High

1155019

ADIPO
Adiponectin

1

20

High-throughput

0.536

High

1181410

P3H1
Prolyl 3-hydroxylase 1

1

3

High-throughput

0.536

High

1347284

FIBIN
Fin bud initiation factor homolog

1

1

High-throughput

0.536

High

1368430

RTN4R
Reticulon-4 receptor

1

1

High-throughput

0.536

High

1368434

SDF2L
Stromal cell-derived factor 2-like protein 1

1

1

High-throughput

0.536

High

1368437

DNJB9
DnaJ homolog subfamily B member 9

1

2

High-throughput

0.536

High

869508

TNFL6
Tumor necrosis factor ligand superfamily member 6

2

1

High-throughput

0.521

High

168439

NCTR3
Natural cytotoxicity triggering receptor 3

1

2

High-throughput

0.489

High

214136

DHH
Desert hedgehog protein

1

1

High-throughput

0.489

High

224509

PI15
Peptidase inhibitor 15

1

2

High-throughput

0.489

High

273778

ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4

1

2

High-throughput

0.489

High

289328

FCN3
Ficolin-3

1

2

High-throughput

0.489

High

405616

HRG
Histidine-rich glycoprotein

1

5

High-throughput

0.489

High

416638

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

1

High-throughput

0.489

High

426122

PPB1
Alkaline phosphatase, placental type

1

1

High-throughput

0.489

High

506886

CFC1
Cryptic protein

1

1

High-throughput

0.489

High

570703

EDN3
Endothelin-3

1

1

High-throughput

0.489

High

593461

PGFRA
Platelet-derived growth factor receptor alpha

1

2

High-throughput

0.489

High

597807

CRIS2
Cysteine-rich secretory protein 2

1

2

High-throughput

0.489

High

935776

MFAP4
Microfibril-associated glycoprotein 4

1

2

High-throughput

0.489

High

953834

C1QT8
Complement C1q tumor necrosis factor-related protein 8

1

20

High-throughput

0.489

High

1030201

IL5RA
Interleukin-5 receptor subunit alpha

1

1

High-throughput

0.489

High

1147400

EPHA7
Ephrin type-A receptor 7

1

2

High-throughput

0.489

High

1160229

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

6

High-throughput

0.489

High

1310277

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.489

High

1333752

TM87A
Transmembrane protein 87A

1

1

High-throughput

0.489

High

1368427

GGH
Gamma-glutamyl hydrolase

1

1

High-throughput

0.489

High

1368431

SIRPD
Signal-regulatory protein delta

1

1

High-throughput

0.489

High

1368435

CBLN4
Cerebellin-4

1

20

High-throughput

0.489

High

1368440

EPDR1
Mammalian ependymin-related protein 1

1

1

High-throughput

0.489

High

1368442

LIPG
Endothelial lipase

1

2

High-throughput

0.489

High

242474

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

185894

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

3

High-throughput

0.457

High

170906

CLGN
Calmegin

1

2

High-throughput

0.445

High

251944

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

3

High-throughput

0.445

High

1150304

TAF1C
TATA box-binding protein-associated factor RNA polymerase I subunit C

1

1

High-throughput

0.445

High

1338601

ZN397
Zinc finger protein 397

1

3

High-throughput

0.445

High

132199

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

High-throughput

0.437

High

218575

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.437

High

342278

BRD1
Bromodomain-containing protein 1

1

1

High-throughput

0.437

High

370423

KNG1
Kininogen-1

1

5

High-throughput

0.437

High

574109

GLUT4
Solute carrier family 2, facilitated glucose transporter member 4

1

3

High-throughput

0.437

High

951790

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

Small-scale

0.437

High

1113893

CUL3
Cullin-3

1

1

High-throughput

0.437

High

1249425

OLFM4
Olfactomedin-4

1

1

High-throughput

0.437

High

1360003

LIPH
Lipase member H

1

2

High-throughput

0.437

High

1368436

T106B
Transmembrane protein 106B

1

3

High-throughput

0.437

High

332233

UCP5
Brain mitochondrial carrier protein 1

1

3

High-throughput

0.407

High

505841

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

1

20

High-throughput

0.407

High

584037

FOSL1
Fos-related antigen 1

1

1

High-throughput

0.407

High

1207959

COL12
Collectin-12

1

11

High-throughput

0.407

High

1310193

SFPA2
Pulmonary surfactant-associated protein A2

1

13

High-throughput

0.407

High

1334303

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

1

1

High-throughput

0.407

High

1368428

CC120
Coiled-coil domain-containing protein 120

1

5

High-throughput

0.407

High

1368432

CHST8
Carbohydrate sulfotransferase 8

3

0

High-throughput

0.347

High

64375

CDHR4
Cadherin-related family member 4

1

0

High-throughput

0.279

Low

341342

ECEL1
Endothelin-converting enzyme-like 1

1

0

High-throughput

0.279

Low

342635

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.279

Low

1248778

LYZL1
Lysozyme-like protein 1

1

0

High-throughput

0.279

Low

467317

CBG
Corticosteroid-binding globulin

1

0

High-throughput

0.249

Low

691307

1433T
14-3-3 protein theta

1

0

High-throughput

0.249

Low

938020

FOXA3
Hepatocyte nuclear factor 3-gamma

1

0

High-throughput

0.249

Low

1034790

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.249

Low

1160429

TAZ
Tafazzin

1

0

High-throughput

0.249

Low

1368438

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

171541

S27A2
Long-chain fatty acid transport protein 2

1

0

High-throughput

0.232

Low

1368433

PACC1
Proton-activated chloride channel

1

0

High-throughput

0.232

Low

1368439

FZD10
Frizzled-10

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025