Interactor 1: SELS (Q9BQE4)
Selenoprotein S (SelS) (VCP-interacting membrane protein)
Gene: SELENOS

Interactor 2: DERL1 (Q9BUN8)
Derlin-1 (Degradation in endoplasmic reticulum protein 1) (DERtrin-1) (Der1-like protein 1)
Gene: DERL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.748

The method score is based on:

Property Details
Experiments 34079125, 22119785, 15215856, 17872946, 16289116, 16186510, 16186509, 21832065
Identification Methods proximity labelling technology, affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0030968 - endoplasmic reticulum unfolded protein response
GO:0030970 - retrograde protein transport, ER to cytosol
GO:0036502 - Derlin-1-VIMP complex
and 6 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 189
Hs

1 251
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024