Protein: NNRD
ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (Carbohydrate kinase domain-containing protein) (NAD(P)HX dehydratase)

Gene: NNRD, NAXD
Organism: Homo sapiens
Interactions: 59
UniProt ID: Q8IW45

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0046496 - nicotinamide nucleotide metabolic process
GO:0047453 - ATP-dependent NAD(P)H-hydrate dehydratase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

226823

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

4

1

High-throughput

0.642

High

950320

KR107
Keratin-associated protein 10-7

3

5

High-throughput

0.616

High

950572

KR108
Keratin-associated protein 10-8

3

5

High-throughput

0.616

High

1210695

KMCP1
Kidney mitochondrial carrier protein 1

2

0

High-throughput

0.602

High

300412

KRT34
Keratin, type I cuticular Ha4

2

1

High-throughput

0.553

High

950183

KR106
Keratin-associated protein 10-6

2

5

High-throughput

0.553

High

1307409

KRA13
Keratin-associated protein 1-3

2

5

High-throughput

0.553

High

1309551

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

1

High-throughput

0.553

High

1309557

UBQL2
Ubiquilin-2

2

1

High-throughput

0.553

High

439777

INSR
Insulin receptor

1

1

High-throughput

0.536

High

465571

IGF1R
Insulin-like growth factor 1 receptor

1

1

High-throughput

0.536

High

685901

KRA59
Keratin-associated protein 5-9

1

6

High-throughput

0.523

High

950823

KR109
Keratin-associated protein 10-9

1

5

High-throughput

0.523

High

1146025

K1H1
Keratin, type I cuticular Ha1

1

1

High-throughput

0.523

High

1277302

NT2NA
Notch homolog 2 N-terminal-like protein A

1

1

High-throughput

0.523

High

1309562

UBQL1
Ubiquilin-1

1

1

High-throughput

0.523

High

535270

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.513

High

667927

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.513

High

778076

VGFR2
Vascular endothelial growth factor receptor 2

1

0

High-throughput

0.513

High

943087

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

944949

RAB38
Ras-related protein Rab-38

1

0

High-throughput

0.513

High

1309560

DD19B
ATP-dependent RNA helicase DDX19B

1

0

High-throughput

0.513

High

170853

CLGN
Calmegin

1

1

High-throughput

0.489

High

427913

ICAM1
Intercellular adhesion molecule 1

1

1

High-throughput

0.489

High

698853

CALX
Calnexin

1

1

High-throughput

0.489

High

1009154

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

1

High-throughput

0.489

High

1252800

NFXL1
NF-X1-type zinc finger protein NFXL1

1

1

High-throughput

0.489

High

1309559

ICAM5
Intercellular adhesion molecule 5

1

1

High-throughput

0.489

High

947222

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

949927

KR103
Keratin-associated protein 10-3

1

5

High-throughput

0.439

High

578681

GLNA
Glutamine synthetase

1

0

High-throughput

0.426

High

651682

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

0

High-throughput

0.426

High

346657

TTC4
Tetratricopeptide repeat protein 4

1

2

High-throughput

0.407

High

1065002

FGL1
Fibrinogen-like protein 1

4

0

High-throughput

0.360

High

1273090

LIGO2
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2

2

0

High-throughput

0.328

High

1309549

NEUFC
Neuferricin

2

0

High-throughput

0.328

High

1008675

PHEX
Phosphate-regulating neutral endopeptidase PHEX

2

0

High-throughput

0.319

High

1309548

EIF1A
Probable RNA-binding protein EIF1AD

2

0

High-throughput

0.313

High

162229

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

0

High-throughput

0.279

Low

225375

ERD23
ER lumen protein-retaining receptor 3

1

0

High-throughput

0.279

Low

302188

NEBL
Nebulette

1

0

High-throughput

0.279

Low

409442

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

0

High-throughput

0.279

Low

964668

DCAF7
DDB1- and CUL4-associated factor 7

1

0

High-throughput

0.279

Low

1143634

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.279

Low

1143741

PON2
Serum paraoxonase/arylesterase 2

1

0

High-throughput

0.279

Low

1205673

ZN311
Zinc finger protein 311

1

0

High-throughput

0.279

Low

1309550

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

0

High-throughput

0.279

Low

1309553

F111A
Serine protease FAM111A

1

0

High-throughput

0.279

Low

1309554

TM209
Transmembrane protein 209

1

0

High-throughput

0.279

Low

1309555

PACC1
Proton-activated chloride channel

1

0

High-throughput

0.279

Low

1309556

CLN6
Ceroid-lipofuscinosis neuronal protein 6

1

0

High-throughput

0.279

Low

1309558

MKLN1
Muskelin

1

0

High-throughput

0.279

Low

1309561

PPT2
Lysosomal thioesterase PPT2

1

0

High-throughput

0.279

Low

832745

BCL6
B-cell lymphoma 6 protein

1

0

High-throughput

0.269

Low

1254526

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

387129

TNNC2
Troponin C, skeletal muscle

1

0

High-throughput

0.232

Low

603666

JUNB
Transcription factor JunB

1

0

High-throughput

0.232

Low

1272700

MAEA
E3 ubiquitin-protein transferase MAEA

1

0

High-throughput

0.232

Low

1309552

HEXI2
Protein HEXIM2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025