HitPredict

Interactor 1: NUD12 (Q9BQG2)
NAD-capped RNA hydrolase NUDT12 (DeNADding enzyme NUDT12) (EC 3.6.1.-) (NADH pyrophosphatase NUDT12) (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12)
Gene: NUDT12

Interactor 2: HSPB8 (Q9UJY1)
Heat shock protein beta-8 (HspB8) (Alpha-crystallin C chain) (E2-induced gene 1 protein) (Heat shock protein family B member 8) (Protein kinase H11) (Small stress protein-like protein HSP22)
Gene: HSPB8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	28514442, 33961781, 32707033
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 462 Hs			1 196
+	Hs
		388597 ANR44_HUMAN (2-170): 2.47e-30: 126: 21.77		HSPB1_HUMAN (1-179): 9.77e-63: 194: 36.67
+	Hs
		358831 ANR44_HUMAN (2-170): 2.47e-30: 126: 21.77		CRYAA_HUMAN (6-187): 8.59e-53: 168: 23.53
+	Hs
		1296437 EHMT2_HUMAN (6-100): 1.28e-09: 62.9: 23.16		HSPB8_HUMAN (1-196): 7.92e-71: 214: 100.00
+	Hs
		388207 ANK1_HUMAN (249-459): 1.48e-14: 78.7: 8.41		HSPB1_HUMAN (1-179): 9.77e-63: 194: 36.67
+	Hs
		388415 ILK_HUMAN (9-100): 3.03e-11: 67.1: 28.26		HSPB1_HUMAN (1-179): 9.77e-63: 194: 36.67
+	Hs
		388725 Q9H4D1_HUMAN (11-103): 1.97e-10: 65.2: 26.88		HSPB1_HUMAN (1-179): 9.77e-63: 194: 36.67