HitPredict

Interactor 1: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Interactor 2: CENPJ (Q9HC77)
Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1)
Gene: CENPJ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	24613305, 29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0005874 - microtubule
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 669 Hs			1 1338
+	Hs
		1268083 LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00		MY18A_HUMAN (521-1158): 4.88e-166: 547: 17.72
+	Hs
		1268099 MYO5C_HUMAN (318-668): 7.57e-17: 87.4: 12.02		MY18A_HUMAN (521-1158): 4.88e-166: 547: 17.72
+	Hs
		1268060 MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67		MY18A_HUMAN (521-1158): 4.88e-166: 547: 17.72
+	Hs
		1051471 DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41		CENPJ_HUMAN (1-1338): 7.36e-158: 512: 100.00
+	Hs
		724989 LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00		MYH9_HUMAN (706-1191): 3.3e-14: 80.5: 10.51
+	Hs
		551822 LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00		DESP_HUMAN (653-1103): 3.01e-09: 64.2: 15.30
+	Dm
		1280413 Q960T6_DROME (305-647): 1.85e-11: 69.6: 17.90		Q9VI72_DROME (900-1337): 2.86e-47: 186: 30.11
+	Hs
		528432 MYH13_HUMAN (161-669): 3.57e-13: 75.4: 11.94		MYH8_HUMAN (356-1218): 4.54e-31: 135: 8.98
+	Hs
		528435 MYH4_HUMAN (261-669): 1.55e-12: 73.1: 12.32		MYH8_HUMAN (356-1218): 4.54e-31: 135: 8.98
+	Hs
		502901 MYH3_HUMAN (321-655): 9.39e-13: 74: 14.93		MYH6_HUMAN (356-1181): 9.56e-31: 134: 10.32
+	Mm
		1322210 TSC1_MOUSE (48-630): 3.36e-32: 135: 13.67		RBCC1_MOUSE (524-1051): 4.19e-11: 69.9: 13.32
+	Rn
		361106 MYH6_RAT (324-644): 1.04e-11: 70.5: 15.01		MYH6_RAT (356-1181): 4.7e-30: 132: 10.91
+	Hs
		502933 MYH3_HUMAN (321-655): 9.39e-13: 74: 14.93		MYH4_HUMAN (70-935): 6.8e-27: 122: 7.61
+	Hs
		522657 MYH4_HUMAN (261-669): 1.55e-12: 73.1: 12.32		MYH7_HUMAN (431-1261): 4.84e-26: 119: 8.67
+	Dm
		404213 MYSA_DROME (329-654): 6.59e-14: 77.9: 14.65		MYSA_DROME (70-889): 5.87e-24: 112: 8.14
+	Hs
		725035 MYO5C_HUMAN (318-668): 7.57e-17: 87.4: 12.02		MYH9_HUMAN (706-1191): 3.3e-14: 80.5: 10.51
+	Rn
		222476 MRCKA_RAT (185-663): 4.24e-19: 94.3: 11.02		MRCKB_RAT (727-1082): 6.88e-12: 72.6: 12.81
+	Hs
		724943 MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67		MYH9_HUMAN (706-1191): 3.3e-14: 80.5: 10.51
+	Dm
		1303379 MYSN_DROME (321-639): 1.56e-12: 73.5: 17.45		MYSN_DROME (332-1038): 7.07e-12: 72.6: 15.53