Protein: CENPF
Centromere protein F (CENP-F) (AH antigen) (Kinetochore protein CENPF) (Mitosin)

Gene: CENPF
Organism: Homo sapiens
Interactions: 130
UniProt ID: P49454

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000775 - chromosome, centromeric region
GO:0000776 - kinetochore
GO:0000785 - chromatin
GO:0000922 - spindle pole

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

883944

NDEL1
Nuclear distribution protein nudE-like 1

3

20

Small-scale

0.672

High

883945

CCD68
Coiled-coil domain-containing protein 68

3

7

High-throughput

0.667

High

881693

FNTB
Protein farnesyltransferase subunit beta

3

0

High-throughput

0.638

High

883948

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

2

16

High-throughput

0.628

High

883971

NEMO
NF-kappa-B essential modulator

2

19

High-throughput

0.628

High

371463

MYC
Myc proto-oncogene protein

2

14

High-throughput

0.611

High

883928

RN166
E3 ubiquitin-protein ligase RNF166

2

20

High-throughput

0.611

High

883923

TCP1L
T-complex protein 10A homolog 1

2

0

High-throughput

0.602

High

883938

MTMR9
Myotubularin-related protein 9

2

4

High-throughput

0.601

High

798843

BRCA1
Breast cancer type 1 susceptibility protein

2

20

High-throughput

0.584

High

883885

H4
Histone H4

2

15

High-throughput

0.584

High

883896

HDAC1
Histone deacetylase 1

2

20

High-throughput

0.584

High

883897

CUL3
Cullin-3

2

20

High-throughput

0.584

High

883950

ANLN
Anillin

2

12

High-throughput

0.584

High

881642

FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

2

0

High-throughput

0.576

High

683406

IKBA
NF-kappa-B inhibitor alpha

1

20

High-throughput

0.536

High

732482

ARRB2
Beta-arrestin-2

1

7

High-throughput

0.536

High

821076

TXLNA
Alpha-taxilin

1

19

High-throughput

0.536

High

848224

MAGA3
Melanoma-associated antigen 3

1

18

High-throughput

0.536

High

853928

KI67
Proliferation marker protein Ki-67

1

20

High-throughput

0.536

High

883883

NU107
Nuclear pore complex protein Nup107

1

1

Small-scale

0.536

High

883894

G3BP1
Ras GTPase-activating protein-binding protein 1

1

6

High-throughput

0.536

High

883907

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.536

High

883914

CSN6
COP9 signalosome complex subunit 6

1

3

High-throughput

0.536

High

883918

SYCE1
Synaptonemal complex central element protein 1

1

4

High-throughput

0.536

High

883925

BRK1
Protein BRICK1

1

2

High-throughput

0.536

High

883931

TMA16
Translation machinery-associated protein 16

1

1

High-throughput

0.536

High

883932

CDCA5
Sororin

1

1

High-throughput

0.536

High

883935

ASPP1
Apoptosis-stimulating of p53 protein 1

1

20

High-throughput

0.536

High

883940

MA7D2
MAP7 domain-containing protein 2

1

19

High-throughput

0.536

High

883961

ALK
ALK tyrosine kinase receptor

2

20

Small-scale

0.533

High

883917

MIRO2
Mitochondrial Rho GTPase 2

2

20

High-throughput

0.521

High

716169

ERP29
Endoplasmic reticulum resident protein 29

1

6

High-throughput

0.515

High

883890

H11
Histone H1.1

1

7

High-throughput

0.515

High

883943

SETD2
Histone-lysine N-methyltransferase SETD2

1

9

High-throughput

0.515

High

455725

H10
Histone H1.0

1

0

High-throughput

0.513

High

883892

MZT1
Mitotic-spindle organizing protein 1

1

0

High-throughput

0.513

High

883913

CENPU
Centromere protein U

1

0

High-throughput

0.513

High

883958

FBXL5
F-box/LRR-repeat protein 5

1

0

High-throughput

0.513

High

883965

POLH
DNA polymerase eta

1

0

High-throughput

0.513

High

883968

COG6
Conserved oligomeric Golgi complex subunit 6

1

0

High-throughput

0.513

High

883924

NU133
Nuclear pore complex protein Nup133

1

2

Small-scale

0.506

High

443263

CDK1
Cyclin-dependent kinase 1

1

17

Small-scale

0.501

High

883880

IMA5
Importin subunit alpha-5

1

3

Small-scale

0.501

High

883929

ESAM
Endothelial cell-selective adhesion molecule

1

11

High-throughput

0.489

High

883936

F167A
Protein FAM167A

1

2

High-throughput

0.489

High

883942

KXDL1
KxDL motif-containing protein 1

1

3

High-throughput

0.489

High

883962

WASF3
Actin-binding protein WASF3

1

12

High-throughput

0.489

High

336376

SVIL
Supervillin

1

18

Small-scale

0.481

High

352364

TOP3B
DNA topoisomerase 3-beta-1

1

2

Small-scale

0.481

High

883878

CENPF
Centromere protein F

1

19

Small-scale

0.481

High

157094

CTRO
Citron Rho-interacting kinase

1

20

High-throughput

0.479

High

222823

PRC1
Protein regulator of cytokinesis 1

1

20

High-throughput

0.479

High

246479

KDM1A
Lysine-specific histone demethylase 1A

1

11

High-throughput

0.479

High

247258

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

16

High-throughput

0.479

High

271983

OBSL1
Obscurin-like protein 1

1

19

High-throughput

0.479

High

302781

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

20

High-throughput

0.479

High

346903

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.479

High

445779

ENOA
Alpha-enolase

1

7

High-throughput

0.479

High

446769

NPM
Nucleophosmin

1

5

Small-scale

0.479

High

460467

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

5

High-throughput

0.479

High

468175

HS90B
Heat shock protein HSP 90-beta

1

14

High-throughput

0.479

High

588184

RFA2
Replication protein A 32 kDa subunit

1

13

High-throughput

0.479

High

694907

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

9

High-throughput

0.479

High

697036

APEX1
DNA repair nuclease/redox regulator APEX1

1

1

High-throughput

0.479

High

764276

CTNA1
Catenin alpha-1

1

7

High-throughput

0.479

High

767401

RADI
Radixin

1

20

High-throughput

0.479

High

767681

RFA3
Replication protein A 14 kDa subunit

1

10

High-throughput

0.479

High

791181

SYUA
Alpha-synuclein

1

4

High-throughput

0.479

High

883879

BAP31
B-cell receptor-associated protein 31

1

14

High-throughput

0.479

High

883881

PLK1
Serine/threonine-protein kinase PLK1

1

6

High-throughput

0.479

High

883882

TERF1
Telomeric repeat-binding factor 1

1

6

High-throughput

0.479

High

883884

RL7A
Large ribosomal subunit protein eL8

1

4

High-throughput

0.479

High

883886

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

8

High-throughput

0.479

High

883887

ACTC
Actin, alpha cardiac muscle 1

1

20

High-throughput

0.479

High

883888

TCPB
T-complex protein 1 subunit beta

1

10

High-throughput

0.479

High

883893

TIF1B
Transcription intermediary factor 1-beta

1

17

High-throughput

0.479

High

883895

BIRC3
Baculoviral IAP repeat-containing protein 3

1

10

High-throughput

0.479

High

883898

CUL4A
Cullin-4A

1

20

High-throughput

0.479

High

883899

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

20

High-throughput

0.479

High

883900

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

18

High-throughput

0.479

High

883901

CUL7
Cullin-7

1

15

High-throughput

0.479

High

883903

KIF14
Kinesin-like protein KIF14

1

20

High-throughput

0.479

High

883904

EEA1
Early endosome antigen 1

1

18

High-throughput

0.479

High

883905

TERF2
Telomeric repeat-binding factor 2

1

6

High-throughput

0.479

High

883906

T22D1
TSC22 domain family protein 1

1

16

High-throughput

0.479

High

883908

AR13B
ADP-ribosylation factor-like protein 13B

1

14

High-throughput

0.479

High

883910

RN123
E3 ubiquitin-protein ligase RNF123

1

20

High-throughput

0.479

High

883912

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

883915

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

9

High-throughput

0.479

High

883916

SLN11
Schlafen family member 11

1

6

High-throughput

0.479

High

883921

FBX22
F-box only protein 22

1

3

High-throughput

0.479

High

883926

P66B
Transcriptional repressor p66-beta

1

1

High-throughput

0.479

High

883927

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

883930

PF21A
PHD finger protein 21A

1

20

High-throughput

0.479

High

883946

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

883947

NANOG
Homeobox protein NANOG

1

8

High-throughput

0.479

High

883951

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

9

High-throughput

0.479

High

883954

NDE1
Nuclear distribution protein nudE homolog 1

1

17

Small-scale

0.479

High

883956

HECW2
E3 ubiquitin-protein ligase HECW2

1

11

High-throughput

0.479

High

883957

ZRAN1
Ubiquitin thioesterase ZRANB1

1

18

High-throughput

0.479

High

883959

RCOR1
REST corepressor 1

1

11

High-throughput

0.479

High

883963

MARE3
Microtubule-associated protein RP/EB family member 3

1

12

High-throughput

0.479

High

883970

MTCH2
Mitochondrial carrier homolog 2

1

8

High-throughput

0.479

High

883911

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

883941

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.458

High

883966

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

883889

CENPE
Centromere-associated protein E

1

7

Small-scale

0.457

High

883952

DISC1
Disrupted in schizophrenia 1 protein

1

9

High-throughput

0.457

High

883964

CHM2B
Charged multivesicular body protein 2b

1

14

High-throughput

0.457

High

129681

CBX4
E3 SUMO-protein ligase CBX4

1

10

High-throughput

0.445

High

429520

JUN
Transcription factor Jun

1

9

High-throughput

0.445

High

883891

HEN2
Helix-loop-helix protein 2

1

3

High-throughput

0.445

High

883909

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

12

Small-scale

0.445

High

883937

CEP63
Centrosomal protein of 63 kDa

1

20

High-throughput

0.445

High

883939

CK5P2
CDK5 regulatory subunit-associated protein 2

1

19

High-throughput

0.445

High

883969

GPC6
Glypican-6 [Cleaved into: Secreted glypican-6]

1

3

High-throughput

0.445

High

72982

WDR64
WD repeat-containing protein 64

1

20

High-throughput

0.437

High

883949

LUC7L
Putative RNA-binding protein Luc7-like 1

1

2

High-throughput

0.437

High

883955

SEP10
Septin-10

1

7

High-throughput

0.437

High

883960

HECD1
E3 ubiquitin-protein ligase HECTD1

1

16

High-throughput

0.437

High

883967

OFUT2
GDP-fucose protein O-fucosyltransferase 2

1

1

High-throughput

0.437

High

883902

MD2BP
MAD2L1-binding protein

1

0

High-throughput

0.426

High

883920

MOT11
Monocarboxylate transporter 11

1

4

High-throughput

0.407

High

883934

NEUL4
Neuralized-like protein 4

1

6

High-throughput

0.407

High

883919

CCD33
Coiled-coil domain-containing protein 33

2

0

High-throughput

0.328

High

883933

MR1L1
MORF4 family-associated protein 1-like 1

1

0

High-throughput

0.279

Low

883953

ACER3
Alkaline ceramidase 3

1

0

High-throughput

0.279

Low

883922

BL1S5
Biogenesis of lysosome-related organelles complex 1 subunit 5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025