HitPredict

Interactor 1: PSDE (O00487)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)
Gene: PSMD14

Interactor 2: DDI1 (Q8WTU0)
Protein DDI1 homolog 1 (EC 3.4.23.-)
Gene: DDI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 310 Hs			1 396
+	Hs
		130934 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		DDI2_HUMAN (1-392): 2.76e-155: 445: 70.93
+	Hs
		849244 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		DDI1_HUMAN (1-396): 4.1e-163: 465: 100.00
+	Hs
		849216 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		DDI2_HUMAN (1-392): 2.76e-155: 445: 70.93
+	Sc
		768185 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		DDI1_YEAST (14-369): 1.01e-91: 284: 29.41
+	Hs
		131106 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL1_HUMAN (5-249): 3.83e-47: 171: 14.74
+	Hs
		131100 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL2_HUMAN (5-249): 4.55e-46: 168: 14.74
+	Dm
		1358677 PSDE_DROME (1-310): 7.15e-114: 333: 88.39		Q9VWD9_DROME (5-249): 3.39e-41: 154: 13.55
+	Hs
		131091 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL4_HUMAN (8-249): 3.58e-43: 160: 14.24
+	Zm
		27878 B4FLQ8_MAIZE (1-309): 4.83e-111: 326: 79.29		A0A1D6JMS0_MAIZE (4-249): 3.7e-41: 154: 17.86
+	Hs
		130790 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		BAG6_HUMAN (4-168): 1.28e-24: 108: 15.25
+	Hs
		130837 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RS27A_HUMAN (5-93): 5.56e-24: 98.8: 17.98
+	Zm
		46881 A0A3L6GBJ0_MAIZE (8-304): 3.94e-71: 226: 18.33		C0PFA7_MAIZE (6-249): 9.94e-49: 175: 17.60
+	Sc
		797465 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		DSK2_YEAST (14-202): 5.04e-25: 106: 17.84
+	Hs
		849284 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		UBQL1_HUMAN (5-249): 3.83e-47: 171: 14.74
+	Hs
		849280 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		UBQL2_HUMAN (5-249): 4.55e-46: 168: 14.74
+	Hs
		176966 EIF3H_HUMAN (23-298): 5.55e-55: 183: 21.05		BAG6_HUMAN (4-168): 1.28e-24: 108: 15.25
+	Dm
		640796 PSMD7_DROME (27-185): 4.64e-35: 131: 23.03		Q9VWD9_DROME (5-249): 3.39e-41: 154: 13.55
+	Hs
		803427 BRCC3_HUMAN (32-188): 1e-41: 148: 25.79		BAG6_HUMAN (4-168): 1.28e-24: 108: 15.25