Protein: HIP1R
Huntingtin-interacting protein 1-related protein (HIP1-related protein) (Huntingtin-interacting protein 12) (HIP-12)

Gene: HIP1R
Organism: Homo sapiens
Interactions: 130
UniProt ID: O75146

Gene Ontology (top 5):
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 - phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

130900

HIP1
Huntingtin-interacting protein 1

5

16

Small-scale

0.935

High

163870

NDC80
Kinetochore protein NDC80 homolog

5

16

High-throughput

0.711

High

271644

HIP1R
Huntingtin-interacting protein 1-related protein

1

16

Small-scale

0.692

High

271656

CLCB
Clathrin light chain B

4

6

Small-scale

0.692

High

271702

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

10

High-throughput

0.691

High

262186

SCN2B
Sodium channel regulatory subunit beta-2

4

1

High-throughput

0.691

High

171640

GAK
Cyclin-G-associated kinase

3

13

High-throughput

0.675

High

271748

PD1L1
Programmed cell death 1 ligand 1

3

2

High-throughput

0.667

High

271666

EPHA1
Ephrin type-A receptor 1

3

4

High-throughput

0.662

High

271655

CLCA
Clathrin light chain A

3

6

Small-scale

0.660

High

271652

ESR1
Estrogen receptor

3

15

High-throughput

0.650

High

271757

EPN1
Epsin-1

1

4

Small-scale

0.647

High

271719

CMTD1
Catechol O-methyltransferase domain-containing protein 1

3

0

High-throughput

0.638

High

271645

PPM1B
Protein phosphatase 1B

2

1

High-throughput

0.628

High

271667

SFPQ
Splicing factor, proline- and glutamine-rich

2

3

High-throughput

0.628

High

271676

APJ
Apelin receptor

2

3

High-throughput

0.628

High

271678

PPM1A
Protein phosphatase 1A

2

1

High-throughput

0.628

High

271706

I13R2
Interleukin-13 receptor subunit alpha-2

2

3

High-throughput

0.628

High

271708

RBP1
RalA-binding protein 1

2

6

High-throughput

0.628

High

271735

REPS1
RalBP1-associated Eps domain-containing protein 1

2

4

High-throughput

0.628

High

271745

S39A9
Zinc transporter ZIP9

2

5

High-throughput

0.628

High

271659

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

8

Small-scale

0.621

High

271698

CLH1
Clathrin heavy chain 1

2

4

Small-scale

0.619

High

271661

TRI27
Zinc finger protein RFP

2

7

High-throughput

0.606

High

271689

ACTB
Actin, cytoplasmic 1

2

18

Small-scale

0.602

High

271671

CD70
CD70 antigen

2

0

High-throughput

0.602

High

271715

LRFN4
Leucine-rich repeat and fibronectin type-III domain-containing protein 4

2

0

High-throughput

0.602

High

271736

STALP
AMSH-like protease

2

0

High-throughput

0.602

High

271668

TNR5
Tumor necrosis factor receptor superfamily member 5

2

5

High-throughput

0.601

High

271646

LYPD3
Ly6/PLAUR domain-containing protein 3

2

0

High-throughput

0.585

High

271691

RHOB
Rho-related GTP-binding protein RhoB

2

9

High-throughput

0.584

High

271663

VCAM1
Vascular cell adhesion protein 1

2

7

High-throughput

0.571

High

132541

UPK1A
Uroplakin-1a

1

8

High-throughput

0.536

High

165871

FFAR1
Free fatty acid receptor 1

1

3

High-throughput

0.536

High

182431

GP182
G-protein coupled receptor 182

1

5

High-throughput

0.536

High

183897

S22A2
Solute carrier family 22 member 2

1

2

High-throughput

0.536

High

271657

PGFRB
Platelet-derived growth factor receptor beta

1

3

High-throughput

0.536

High

271665

FPR1
fMet-Leu-Phe receptor

1

4

High-throughput

0.536

High

271670

CCR1
C-C chemokine receptor type 1

1

4

High-throughput

0.536

High

271677

MYH9
Myosin-9

1

16

High-throughput

0.536

High

271682

CAZA2
F-actin-capping protein subunit alpha-2

1

5

High-throughput

0.536

High

271692

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

1

High-throughput

0.536

High

271697

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

3

High-throughput

0.536

High

271700

AP1B1
AP-1 complex subunit beta-1

1

5

High-throughput

0.536

High

271704

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

17

High-throughput

0.536

High

271714

KLC3
Kinesin light chain 3

1

3

High-throughput

0.536

High

271730

BSND
Barttin

1

1

High-throughput

0.536

High

271731

AQP3
Aquaporin-3

1

3

High-throughput

0.536

High

271737

MYO19
Unconventional myosin-XIX

1

17

High-throughput

0.536

High

271740

WNK3
Serine/threonine-protein kinase WNK3

1

3

High-throughput

0.536

High

271742

PAAT
ATPase PAAT

1

1

High-throughput

0.536

High

271747

GTSE1
G2 and S phase-expressed protein 1

1

3

High-throughput

0.536

High

271752

LIMA1
LIM domain and actin-binding protein 1

1

4

High-throughput

0.536

High

271753

GLSL
Glutaminase liver isoform, mitochondrial

1

5

High-throughput

0.536

High

208933

CYB5B
Cytochrome b5 type B

1

0

High-throughput

0.513

High

230932

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

High-throughput

0.513

High

271650

GLPA
Glycophorin-A

1

0

High-throughput

0.513

High

271654

SYPH
Synaptophysin

1

0

High-throughput

0.513

High

271658

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

271673

SDC2
Syndecan-2

1

0

High-throughput

0.513

High

271680

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.513

High

271681

S15A1
Solute carrier family 15 member 1

1

0

High-throughput

0.513

High

271684

PTH2R
Parathyroid hormone 2 receptor

1

0

High-throughput

0.513

High

271687

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

271699

VMAT2
Synaptic vesicular amine transporter

1

0

High-throughput

0.513

High

271709

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.513

High

271717

T150A
Transmembrane protein 150A

1

0

High-throughput

0.513

High

271723

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

271728

HUMMR
Protein MGARP

1

0

High-throughput

0.513

High

271739

CDHR2
Cadherin-related family member 2

1

0

High-throughput

0.513

High

271744

GTR9
Solute carrier family 2, facilitated glucose transporter member 9

1

0

High-throughput

0.513

High

271746

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.513

High

271703

SNW1
SNW domain-containing protein 1

1

4

High-throughput

0.489

High

271738

CDC5L
Cell division cycle 5-like protein

1

3

High-throughput

0.489

High

271754

PHF11
PHD finger protein 11

1

2

High-throughput

0.489

High

189343

STX7
Syntaxin-7

1

2

High-throughput

0.479

High

271647

PCNT
Pericentrin

1

18

High-throughput

0.479

High

271648

DIRA3
GTP-binding protein Di-Ras3

1

4

High-throughput

0.479

High

271649

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.479

High

271651

FINC
Fibronectin

1

5

High-throughput

0.479

High

271653

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.479

High

271660

ITA4
Integrin alpha-4

1

4

High-throughput

0.479

High

271679

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

271683

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

271685

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.479

High

271686

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

13

High-throughput

0.479

High

271693

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

4

High-throughput

0.479

High

271694

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

3

High-throughput

0.479

High

271695

AP2B1
AP-2 complex subunit beta

1

5

High-throughput

0.479

High

271696

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

271707

SMC1A
Structural maintenance of chromosomes protein 1A

1

14

High-throughput

0.479

High

271722

CXD3
Gap junction delta-3 protein

1

4

High-throughput

0.479

High

271732

ESR2
Estrogen receptor beta

1

14

High-throughput

0.479

High

271734

SH3K1
SH3 domain-containing kinase-binding protein 1

1

6

Small-scale

0.479

High

271741

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

271743

RHOF
Rho-related GTP-binding protein RhoF

1

11

High-throughput

0.479

High

271749

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

271751

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

271755

SMC3
Structural maintenance of chromosomes protein 3

1

14

High-throughput

0.479

High

271701

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

271710

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

271712

AP1AR
AP-1 complex-associated regulatory protein

1

0

High-throughput

0.458

High

271713

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

271724

STAG2
Cohesin subunit SA-2

1

0

High-throughput

0.458

High

254676

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.445

High

271672

CD80
T-lymphocyte activation antigen CD80

1

3

High-throughput

0.445

High

271674

CD68
Macrosialin

1

1

High-throughput

0.445

High

271688

CD81
CD81 antigen

1

7

Small-scale

0.445

High

271727

LIRB4
Leukocyte immunoglobulin-like receptor subfamily B member 4

1

2

High-throughput

0.445

High

271733

IGSF8
Immunoglobulin superfamily member 8

1

5

High-throughput

0.445

High

104940

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

271662

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.437

High

271669

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

271675

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

271690

WDR5
WD repeat-containing protein 5

1

4

High-throughput

0.437

High

271705

BOP1
Ribosome biogenesis protein BOP1

1

5

Small-scale

0.437

High

271716

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.437

High

271718

ZCH18
Zinc finger CCCH domain-containing protein 18

1

8

High-throughput

0.437

High

271664

KLK2
Kallikrein-2

1

2

High-throughput

0.407

High

271720

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

1

High-throughput

0.407

High

271726

TEX29
Testis-expressed protein 29

3

0

High-throughput

0.347

High

60696

F234B
Protein FAM234B

2

0

High-throughput

0.328

High

271725

MFD4A
Major facilitator superfamily domain-containing protein 4A

2

0

High-throughput

0.328

High

271729

TM171
Transmembrane protein 171

2

0

High-throughput

0.318

High

271750

TFP11
Tuftelin-interacting protein 11

2

0

High-throughput

0.316

High

71185

HIDE1
Protein HIDE1

1

0

High-throughput

0.279

Low

271711

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.279

Low

271721

CKLF8
CKLF-like MARVEL transmembrane domain-containing protein 8

1

0

High-throughput

0.279

Low

271756

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025