HitPredict

Interactor 1: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Interactor 2: X5DP35 (X5DP35)
NudE neurodevelopment protein 1 isoform A
Gene: NDE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	24722188
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005874 - microtubule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 669 Hs			1 339
+	Hs
		1310186 LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00		NDE1_HUMAN (1-276): 1.58e-54: 183: 96.01
+	Hs
		724989 LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00		MYH9_HUMAN (2-212): 2.69e-30: 123: 18.48
+	Hs
		1326043 MTCL1_HUMAN (56-644): 5.72e-34: 141: 14.24		NDEL1_HUMAN (3-276): 5.34e-55: 184: 59.21
+	Hs
		1012572 CGNL1_HUMAN (321-645): 5.23e-13: 74.7: 21.88		NDE1_HUMAN (1-276): 1.58e-54: 183: 96.01
+	Mm
		139900 DCTN1_MOUSE (88-572): 4.8e-12: 71.6: 11.02		NDEL1_MOUSE (3-276): 7.6e-55: 184: 58.85
+	Hs
		1268126 MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67		MRCKB_HUMAN (2-288): 2.78e-46: 170: 14.01
+	Hs
		1148978 MYO5C_HUMAN (318-668): 7.57e-17: 87.4: 12.02		CYTSA_HUMAN (2-255): 1.06e-36: 142: 18.69
+	Hs
		1051322 DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41		CYTSA_HUMAN (2-255): 1.06e-36: 142: 18.69
+	Hs
		1148939 MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67		CYTSA_HUMAN (2-255): 1.06e-36: 142: 18.69
+	Hs
		725035 MYO5C_HUMAN (318-668): 7.57e-17: 87.4: 12.02		MYH9_HUMAN (2-212): 2.69e-30: 123: 18.48
+	Hs
		1078856 ITSN1_HUMAN (75-640): 4.07e-22: 104: 13.88		MYH14_HUMAN (2-211): 5.77e-22: 99.2: 17.62
+	Hs
		724943 MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67		MYH9_HUMAN (2-212): 2.69e-30: 123: 18.48
+	Mm
		93570 DESP_MOUSE (337-641): 2.9e-11: 69.3: 18.65		MYH9_MOUSE (2-212): 1.66e-29: 121: 17.54
+	Dm
		1303379 MYSN_DROME (321-639): 1.56e-12: 73.5: 17.45		MYSN_DROME (2-210): 4.53e-27: 114: 15.79
+	Hs
		725097 MYH11_HUMAN (141-564): 3.93e-11: 68.9: 11.53		MYH10_HUMAN (2-212): 5.08e-26: 111: 19.43
+	Hs
		1078923 ITSN1_HUMAN (75-640): 4.07e-22: 104: 13.88		EP15R_HUMAN (52-287): 6.33e-13: 71.9: 15.42
+	Hs
		61738 A6H8W8_HUMAN (71-636): 7.43e-22: 103: 13.52		EP15R_HUMAN (52-287): 6.33e-13: 71.9: 15.42
+	Rn
		222472 MRCKA_RAT (185-663): 4.24e-19: 94.3: 11.02		MRCKA_RAT (14-201): 1.54e-12: 70.7: 16.24
+	Rn
		222476 MRCKA_RAT (185-663): 4.24e-19: 94.3: 11.02		MRCKB_RAT (5-188): 1.6e-09: 61.5: 16.13
+	Mm
		1141846 ITSN1_MOUSE (3-554): 8.1e-12: 70.8: 12.08		EP15R_MOUSE (52-243): 1.98e-11: 67.2: 15.31