HitPredict

Interactor 1: PSDE (O00487)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)
Gene: PSMD14

Interactor 2: UBQL1 (Q9UMX0)
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Gene: UBQLN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	27114451, 17323924
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	GO:0000502 - proteasome complex GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 310 Hs			1 589
+	Hs
		131100 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Dm
		1358677 PSDE_DROME (1-310): 7.15e-114: 333: 88.39		Q9VWD9_DROME (30-582): 3.32e-135: 407: 47.39
+	Hs
		131091 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL4_HUMAN (28-589): 1.35e-135: 409: 57.64
+	Zm
		27878 B4FLQ8_MAIZE (1-309): 4.83e-111: 326: 79.29		A0A1D6JMS0_MAIZE (30-586): 1.41e-108: 338: 29.74
+	Hs
		849284 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		UBQL1_HUMAN (1-589): 1.23e-174: 509: 100.00
+	Zm
		46881 A0A3L6GBJ0_MAIZE (8-304): 3.94e-71: 226: 18.33		C0PFA7_MAIZE (44-586): 6.17e-109: 339: 29.29
+	Hs
		849280 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Dm
		640796 PSMD7_DROME (27-185): 4.64e-35: 131: 23.03		Q9VWD9_DROME (30-582): 3.32e-135: 407: 47.39
+	Hs
		131017 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		DDI1_HUMAN (47-318): 6.39e-53: 187: 15.60
+	Hs
		130934 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		DDI2_HUMAN (47-318): 2.03e-49: 178: 13.52
+	Hs
		130790 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		BAG6_HUMAN (25-536): 2.14e-33: 138: 14.66
+	Hs
		130838 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Sc
		697094 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		RAD23_YEAST (45-419): 1.17e-31: 128: 17.73
+	Sc
		797465 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		DSK2_YEAST (36-243): 8.16e-32: 128: 30.73
+	Hs
		130837 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68
+	Hs
		176966 EIF3H_HUMAN (23-298): 5.55e-55: 183: 21.05		BAG6_HUMAN (25-536): 2.14e-33: 138: 14.66
+	Hs
		849244 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		DDI1_HUMAN (47-318): 6.39e-53: 187: 15.60
+	Hs
		849216 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		DDI2_HUMAN (47-318): 2.03e-49: 178: 13.52
+	Hs
		803427 BRCC3_HUMAN (32-188): 1e-41: 148: 25.79		BAG6_HUMAN (25-536): 2.14e-33: 138: 14.66
+	Sc
		697121 RPN8_YEAST (29-185): 1.1e-11: 66.7: 26.38		RAD23_YEAST (45-419): 1.17e-31: 128: 17.73