Protein: CLIC4
Chloride intracellular channel protein 4 (Glutaredoxin-like oxidoreductase CLIC4) (EC 1.8.-.-) (Intracellular chloride ion channel protein p64H1)

Gene: CLIC4
Organism: Homo sapiens
Interactions: 48
UniProt ID: Q9Y696

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001886 - endothelial cell morphogenesis
GO:0005254 - chloride channel activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1399293

CLIC6
Chloride intracellular channel protein 6

4

13

High-throughput

0.905

High

184048

CLIC2
Chloride intracellular channel protein 2

3

14

High-throughput

0.861

High

1453102

CLIC5
Chloride intracellular channel protein 5

3

14

High-throughput

0.861

High

1195341

TPRN
Taperin

5

3

High-throughput

0.717

High

373644

MYC
Myc proto-oncogene protein

2

2

High-throughput

0.584

High

468964

HS90B
Heat shock protein HSP 90-beta

1

2

High-throughput

0.541

High

427966

ICAM1
Intercellular adhesion molecule 1

1

1

High-throughput

0.536

High

1491816

SAR1B
Small COPII coat GTPase SAR1B

1

4

High-throughput

0.536

High

1049075

REL
Proto-oncogene c-Rel

1

0

High-throughput

0.518

High

364098

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.513

High

1042948

ERCC6
DNA excision repair protein ERCC-6

1

0

High-throughput

0.480

High

243441

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

412900

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

538185

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

583046

EZRI
Ezrin

1

4

Small-scale

0.479

High

631048

RAB4A
Ras-related protein Rab-4A

1

2

High-throughput

0.479

High

659651

CRCM
Colorectal mutant cancer protein

1

1

High-throughput

0.479

High

668096

CDK2
Cyclin-dependent kinase 2

1

1

High-throughput

0.479

High

935366

TERA
Transitional endoplasmic reticulum ATPase

1

6

High-throughput

0.479

High

945130

RAB25
Ras-related protein Rab-25

1

2

High-throughput

0.479

High

972186

1433E
14-3-3 protein epsilon

1

4

Small-scale

0.479

High

976702

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.479

High

986841

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.479

High

993406

ACTG
Actin, cytoplasmic 2

1

3

High-throughput

0.479

High

1101125

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.479

High

1156921

E2F4
Transcription factor E2F4

1

1

High-throughput

0.479

High

1256302

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

1335122

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1360856

ASB11
Ankyrin repeat and SOCS box protein 11

1

1

High-throughput

0.479

High

1360974

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.479

High

1364752

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

1367707

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1459489

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

459359

CATL1
Procathepsin L

1

0

High-throughput

0.458

High

487940

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

724228

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.458

High

774738

BASI
Basigin

1

0

High-throughput

0.458

High

791881

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

1162645

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.458

High

404972

PRIO
Major prion protein

1

1

High-throughput

0.445

High

1227799

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.445

High

106935

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

590157

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

696997

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

769643

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

887481

CEBPD
CCAAT/enhancer-binding protein delta

1

5

Small-scale

0.437

High

530680

TAU
Microtubule-associated protein tau

1

0

Small-scale

0.426

High

1429422

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025