HitPredict

Interactor 1: PCGF1 (Q9BSM1)
Polycomb group RING finger protein 1 (Nervous system Polycomb-1) (NSPc1) (RING finger protein 68)
Gene: PCGF1

Interactor 2: KDM2A (Q9Y2K7)
Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A)
Gene: KDM2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 259 Hs			1 1162
+	Hs
		1245590 PCGF1_HUMAN (1-259): 4.13e-82: 248: 100.00		KDM2B_HUMAN (15-1162): 0: 1040: 37.75
+	Mm
		1158236 PCGF1_MOUSE (1-259): 1.69e-82: 249: 98.07		KDM2B_MOUSE (1-1162): 0: 1038: 37.73
+	Hs
		718034 BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29		KDM2B_HUMAN (15-1162): 0: 1040: 37.75
+	Mm
		639474 BMI1_MOUSE (30-255): 1.56e-62: 200: 35.59		KDM2B_MOUSE (1-1162): 0: 1038: 37.73
+	Hs
		718413 PCGF2_HUMAN (30-255): 4.65e-59: 192: 35.57		KDM2B_HUMAN (15-1162): 0: 1040: 37.75
+	Hs
		1108521 PCGF3_HUMAN (32-257): 1.89e-56: 182: 38.68		KDM2B_HUMAN (15-1162): 0: 1040: 37.75
+	Hs
		1245594 PCGF6_HUMAN (26-252): 6.21e-45: 156: 36.05		KDM2B_HUMAN (15-1162): 0: 1040: 37.75
+	Hs
		1197574 PCGF5_HUMAN (30-257): 3.38e-44: 151: 29.41		KDM2B_HUMAN (15-1162): 0: 1040: 37.75
+	Hs
		1245587 RING2_HUMAN (24-259): 7.12e-39: 140: 16.88		KDM2B_HUMAN (15-1162): 0: 1040: 37.75
+	Mm
		1158239 RING2_MOUSE (24-259): 5.08e-39: 140: 16.88		KDM2B_MOUSE (1-1162): 0: 1038: 37.73
+	Mm
		193408 RING1_MOUSE (24-155): 5.39e-33: 125: 20.59		KDM2B_MOUSE (1-1162): 0: 1038: 37.73
+	Hs
		987996 RING1_HUMAN (24-155): 3.14e-32: 123: 20.59		KDM2B_HUMAN (15-1162): 0: 1040: 37.75
+	Hs
		718320 BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29		PHF8_HUMAN (12-406): 1.45e-164: 517: 37.69
+	Hs
		1019385 TRI26_HUMAN (32-223): 6.79e-32: 124: 19.90		PHF8_HUMAN (12-406): 1.45e-164: 517: 37.69
+	Hs
		717733 BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29		KMT2A_HUMAN (360-609): 1.68e-47: 188: 20.73
+	Hs
		975311 RING2_HUMAN (24-259): 7.12e-39: 140: 16.88		KMT2A_HUMAN (360-609): 1.68e-47: 188: 20.73
+	Hs
		584946 RO52_HUMAN (32-226): 9.58e-36: 134: 18.61		SKP2_HUMAN (805-1151): 6.12e-48: 179: 19.24
+	Dm
		627171 SUZ2_DROME (13-254): 7.25e-51: 180: 26.61		JHD1_DROME (431-568): 5.89e-28: 124: 27.54
+	Dm
		728809 PSC_DROME (26-256): 4.12e-50: 178: 28.63		JHD1_DROME (431-568): 5.89e-28: 124: 27.54
+	Dm
		1367224 Q9VV77_DROME (32-257): 1.29e-53: 174: 39.30		JHD1_DROME (431-568): 5.89e-28: 124: 27.54