Protein: RBM5
RNA-binding protein 5 (Protein G15) (Putative tumor suppressor LUCA15) (RNA-binding motif protein 5) (Renal carcinoma antigen NY-REN-9)

Gene: RBM5
Organism: Homo sapiens
Interactions: 145
UniProt ID: P52756

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0000398 - mRNA splicing, via spliceosome
GO:0003677 - DNA binding
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

207485

DHX15
ATP-dependent RNA helicase DHX15

3

14

Small-scale

0.890

High

913943

U2AFM
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2

3

2

High-throughput

0.861

High

913978

SPF45
Splicing factor 45

3

20

High-throughput

0.855

High

485591

RU2A
U2 small nuclear ribonucleoprotein A'

2

1

High-throughput

0.789

High

685468

U2AF2
Splicing factor U2AF 65 kDa subunit

1

20

Small-scale

0.757

High

175624

SR140
U2 snRNP-associated SURP motif-containing protein

1

15

High-throughput

0.740

High

74456

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

20

High-throughput

0.691

High

625260

CSK22
Casein kinase II subunit alpha'

1

13

High-throughput

0.691

High

658048

RS3
Small ribosomal subunit protein uS3

1

4

High-throughput

0.691

High

913922

SRSF4
Serine/arginine-rich splicing factor 4

1

20

High-throughput

0.691

High

913929

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.691

High

913939

SF3B3
Splicing factor 3B subunit 3

1

3

High-throughput

0.691

High

914001

PRP19
Pre-mRNA-processing factor 19

3

11

Small-scale

0.690

High

913974

H2B1H
Histone H2B type 1-H

1

4

High-throughput

0.665

High

913963

NEK7
Serine/threonine-protein kinase Nek7

1

9

High-throughput

0.665

High

913925

SF3A3
Splicing factor 3A subunit 3

1

0

High-throughput

0.656

High

914006

MARF1
Meiosis regulator and mRNA stability factor 1

1

0

High-throughput

0.656

High

348243

DCMC
Malonyl-CoA decarboxylase, mitochondrial

3

0

High-throughput

0.636

High

168658

CSKP
Peripheral plasma membrane protein CASK

1

1

High-throughput

0.621

High

913970

DDX17
Probable ATP-dependent RNA helicase DDX17

1

12

High-throughput

0.621

High

913980

RBM14
RNA-binding protein 14

1

18

High-throughput

0.621

High

157125

CTRO
Citron Rho-interacting kinase

1

12

High-throughput

0.618

High

289473

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

20

Small-scale

0.618

High

400521

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

11

High-throughput

0.618

High

485010

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

20

High-throughput

0.618

High

913924

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

17

High-throughput

0.618

High

913932

DHX8
ATP-dependent RNA helicase DHX8

1

17

High-throughput

0.618

High

913934

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

17

High-throughput

0.618

High

913940

SF3A2
Splicing factor 3A subunit 2

1

7

High-throughput

0.618

High

913944

ELAV1
ELAV-like protein 1

1

19

High-throughput

0.618

High

913951

H2B2C
Putative histone H2B type 2-C

1

4

High-throughput

0.618

High

913972

CELF1
CUGBP Elav-like family member 1

1

20

High-throughput

0.618

High

913986

DDX23
Probable ATP-dependent RNA helicase DDX23

1

17

High-throughput

0.618

High

913992

DDX21
Nucleolar RNA helicase 2

1

17

High-throughput

0.618

High

913999

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.618

High

913936

SUZ12
Polycomb protein SUZ12

2

2

High-throughput

0.611

High

914000

FBW1B
F-box/WD repeat-containing protein 11

2

13

High-throughput

0.611

High

913941

SF01
Splicing factor 1

1

8

High-throughput

0.590

High

913948

PHF19
PHD finger protein 19

1

0

High-throughput

0.586

High

913990

LN28A
Protein lin-28 homolog A

1

20

High-throughput

0.575

High

395740

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

893678

MEOX1
Homeobox protein MOX-1

1

4

High-throughput

0.568

High

913955

ZDH17
Palmitoyltransferase ZDHHC17

1

2

High-throughput

0.541

High

913988

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

5

High-throughput

0.541

High

123641

MYO1C
Unconventional myosin-Ic

1

3

High-throughput

0.536

High

219940

XRCC3
DNA repair protein XRCC3

1

2

High-throughput

0.536

High

539308

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

2

High-throughput

0.536

High

595356

H15
Histone H1.5

1

8

High-throughput

0.536

High

809540

RS19
Small ribosomal subunit protein eS19

1

1

High-throughput

0.536

High

866923

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.536

High

913914

RL15
Large ribosomal subunit protein eL15

1

1

High-throughput

0.536

High

913918

RL19
Large ribosomal subunit protein eL19

1

3

High-throughput

0.536

High

913931

FHL2
Four and a half LIM domains protein 2

1

1

High-throughput

0.536

High

913950

KDM4D
Lysine-specific demethylase 4D

1

1

High-throughput

0.536

High

913953

PRP8
Pre-mRNA-processing-splicing factor 8

1

2

Small-scale

0.536

High

913956

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

5

High-throughput

0.536

High

913961

ARI1B
AT-rich interactive domain-containing protein 1B

1

3

High-throughput

0.536

High

913973

CSN5
COP9 signalosome complex subunit 5

1

7

High-throughput

0.536

High

913996

SIR5
NAD-dependent protein deacylase sirtuin-5, mitochondrial

1

9

High-throughput

0.536

High

914003

FBW1A
F-box/WD repeat-containing protein 1A

1

14

High-throughput

0.536

High

914002

POMP
Proteasome maturation protein

1

0

High-throughput

0.518

High

532471

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.515

High

387391

APOE
Apolipoprotein E

1

1

High-throughput

0.515

High

697813

CALR
Calreticulin

1

3

High-throughput

0.515

High

787947

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

2

High-throughput

0.515

High

788872

TGFR2
TGF-beta receptor type-2

1

1

High-throughput

0.515

High

843404

HD
Huntingtin

1

6

High-throughput

0.515

High

913971

KLK6
Kallikrein-6

1

1

High-throughput

0.515

High

62313

A4FU77
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

12

Small-scale

0.514

High

341916

CEP43
Centrosomal protein 43

1

0

High-throughput

0.513

High

399555

VTNC
Vitronectin

1

0

High-throughput

0.513

High

913916

RUXE
Small nuclear ribonucleoprotein E

1

0

High-throughput

0.513

High

913976

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

344523

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

2

High-throughput

0.508

High

408755

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

3

High-throughput

0.508

High

913921

B2CL1
Bcl-2-like protein 1

1

1

High-throughput

0.508

High

913927

ILF3
Interleukin enhancer-binding factor 3

1

20

High-throughput

0.508

High

913985

MEP50
Methylosome protein WDR77

1

12

High-throughput

0.508

High

914004

WBP11
WW domain-binding protein 11

1

5

High-throughput

0.508

High

913935

EMC2
ER membrane protein complex subunit 2

1

5

High-throughput

0.489

High

913958

EMC5
ER membrane protein complex subunit 5

1

2

High-throughput

0.489

High

893765

MEOX2
Homeobox protein MOX-2

1

4

High-throughput

0.481

High

913942

MED1
Mediator of RNA polymerase II transcription subunit 1

1

4

High-throughput

0.481

High

913962

CIP2A
Protein CIP2A

1

1

Small-scale

0.481

High

913969

CBP
CREB-binding protein

1

6

Small-scale

0.481

High

913984

PKP2
Plakophilin-2

1

6

High-throughput

0.481

High

913989

NDEL1
Nuclear distribution protein nudE-like 1

1

10

High-throughput

0.481

High

128879

MEN1
Menin

1

4

High-throughput

0.479

High

142908

NFIB
Nuclear factor 1 B-type

1

7

High-throughput

0.479

High

182259

WDR46
WD repeat-containing protein 46

1

11

High-throughput

0.479

High

337322

PARN
Poly(A)-specific ribonuclease PARN

1

2

High-throughput

0.479

High

349885

SNAI1
Zinc finger protein SNAI1

1

8

High-throughput

0.479

High

371534

MYC
Myc proto-oncogene protein

1

18

High-throughput

0.479

High

473873

NFIC
Nuclear factor 1 C-type

1

8

High-throughput

0.479

High

657518

GCSP
Glycine dehydrogenase

1

4

High-throughput

0.479

High

809980

RL3
Large ribosomal subunit protein uL3

1

3

High-throughput

0.479

High

872102

SOX2
Transcription factor SOX-2

1

5

High-throughput

0.479

High

886664

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.479

High

898559

RL14
Large ribosomal subunit protein eL14

1

2

High-throughput

0.479

High

904488

MECP2
Methyl-CpG-binding protein 2

1

9

High-throughput

0.479

High

913915

RS8
Small ribosomal subunit protein eS8

1

1

High-throughput

0.479

High

913917

H4
Histone H4

1

3

High-throughput

0.479

High

913919

VIGLN
Vigilin

1

20

High-throughput

0.479

High

913920

TF65
Transcription factor p65

1

4

High-throughput

0.479

High

913923

NFIA
Nuclear factor 1 A-type

1

8

High-throughput

0.479

High

913926

TP53B
TP53-binding protein 1

1

6

High-throughput

0.479

High

913928

NFX1
Transcriptional repressor NF-X1

1

6

High-throughput

0.479

High

913930

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

913937

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

913945

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

3

High-throughput

0.479

High

913954

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.479

High

913957

CCAR2
Cell cycle and apoptosis regulator protein 2

1

4

Small-scale

0.479

High

913959

CGAS
Cyclic GMP-AMP synthase

1

2

Small-scale

0.479

High

913964

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

4

High-throughput

0.479

High

913966

ASB11
Ankyrin repeat and SOCS box protein 11

1

1

High-throughput

0.479

High

913967

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

4

High-throughput

0.479

High

913968

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

913975

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

15

High-throughput

0.479

High

913979

SNX27
Sorting nexin-27

1

7

High-throughput

0.479

High

913981

CDC5L
Cell division cycle 5-like protein

1

4

High-throughput

0.479

High

913982

RING2
E3 ubiquitin-protein ligase RING2

1

18

High-throughput

0.479

High

913983

ANM1
Protein arginine N-methyltransferase 1

1

9

High-throughput

0.479

High

913987

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.479

High

913993

RNC
Ribonuclease 3

1

7

High-throughput

0.479

High

913994

RAD18
E3 ubiquitin-protein ligase RAD18

1

2

High-throughput

0.479

High

913995

ARL8B
ADP-ribosylation factor-like protein 8B

1

6

High-throughput

0.479

High

913997

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

913998

NXF1
Nuclear RNA export factor 1

1

4

High-throughput

0.479

High

914005

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

4

High-throughput

0.479

High

914007

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

4

High-throughput

0.479

High

221247

DCX
Neuronal migration protein doublecortin

1

0

High-throughput

0.460

High

892652

DNLI4
DNA ligase 4

1

0

High-throughput

0.460

High

913938

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.460

High

913947

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.460

High

913949

RIF1
Telomere-associated protein RIF1

1

6

High-throughput

0.457

High

913952

Q6FHY5
MEOX2 protein

1

4

High-throughput

0.457

High

529394

TAU
Microtubule-associated protein tau

1

15

High-throughput

0.445

High

913933

CASP8
Caspase-8

1

2

High-throughput

0.445

High

913946

KIF19
Kinesin-like protein KIF19

1

2

High-throughput

0.439

High

913991

KIF9
Kinesin-like protein KIF9

1

8

High-throughput

0.439

High

913977

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.437

High

72760

B0UZZ8
WD repeat-containing protein 46

1

11

High-throughput

0.407

High

87386

OSCRI
SCRIB overlapping open reading frame protein

1

4

High-throughput

0.407

High

913960

MOT11
Monocarboxylate transporter 11

1

2

High-throughput

0.407

High

913965

PAR3L
Partitioning defective 3 homolog B

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025