HitPredict

Interactor 1: BIN1 (O00499)
Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Box-dependent myc-interacting protein 1) (Bridging integrator 1)
Gene: BIN1

Interactor 2: RIN3 (Q8TB24)
Ras and Rab interactor 3 (Ras interaction/interference protein 3)
Gene: RIN3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.713

Property	Details
Experiments	32552912, 12972505, 35271311, 35241726
Identification Methods	affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006897 - endocytosis GO:0030424 - axon GO:0030425 - dendrite and 1 others more... GO:0031982 - vesicle
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 593 Hs			1 985
+	Hs
		1167810 DNMBP_HUMAN (17-591): 7.98e-54: 200: 16.93		RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00
+	Hs
		1251926 BIN3_HUMAN (32-289): 1.84e-34: 132: 16.73		RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00
+	Hs
		66539 A8K5Y2_HUMAN (44-592): 1.37e-21: 101: 15.13		RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00
+	Hs
		1251932 ITSN2_HUMAN (2-593): 2.37e-12: 72.5: 11.45		RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00
+	Hs
		131258 BIN1_HUMAN (1-593): 1.03e-133: 404: 100.00		Q6NSK7_HUMAN (1-497): 1.57e-56: 213: 65.19
+	Hs
		131177 BIN1_HUMAN (1-593): 1.03e-133: 404: 100.00		SYNJ2_HUMAN (181-524): 2.35e-51: 199: 19.77
+	Rn
		139991 BIN1_RAT (1-592): 2.1e-127: 388: 93.59		SYNJ1_RAT (73-492): 6.56e-11: 68.7: 10.09
+	Hs
		827751 AMPH_HUMAN (44-592): 1.49e-21: 101: 15.13		Q6NSK7_HUMAN (1-497): 1.57e-56: 213: 65.19
+	Hs
		1155937 ITSN2_HUMAN (2-593): 2.37e-12: 72.5: 11.45		Q6NSK7_HUMAN (1-497): 1.57e-56: 213: 65.19
+	Hs
		1078842 ITSN1_HUMAN (3-591): 1.85e-11: 69.4: 13.69		Q6NSK7_HUMAN (1-497): 1.57e-56: 213: 65.19
+	Hs
		166056 ITSN2_HUMAN (2-593): 2.37e-12: 72.5: 11.45		SYNJ2_HUMAN (181-524): 2.35e-51: 199: 19.77
+	Hs
		166049 ITSN1_HUMAN (3-591): 1.85e-11: 69.4: 13.69		SYNJ2_HUMAN (181-524): 2.35e-51: 199: 19.77
+	Dm
		113976 M9PB30_DROME (284-522): 2.63e-10: 65.9: 14.29		M9PB30_DROME (9-582): 8.24e-25: 114: 7.35
+	Hs
		203213 AMPH_HUMAN (44-592): 1.49e-21: 101: 15.13		SYNJ1_HUMAN (311-736): 7.31e-12: 71.8: 11.24
+	Hs
		1044770 ITSN1_HUMAN (3-591): 1.85e-11: 69.4: 13.69		RIN1_HUMAN (6-327): 3.07e-21: 101: 26.32
+	Rn
		139978 AMPH_RAT (44-592): 1.56e-19: 94.9: 16.52		SYNJ1_RAT (73-492): 6.56e-11: 68.7: 10.09
+	Hs
		203228 ITSN1_HUMAN (3-591): 1.85e-11: 69.4: 13.69		SYNJ1_HUMAN (311-736): 7.31e-12: 71.8: 11.24
+	Mm
		1351630 PCLO_MOUSE (267-550): 8.57e-12: 70.9: 13.24		PCLO_MOUSE (186-546): 9.45e-10: 65.1: 13.85