HitPredict

Interactor 1: DDX23 (Q9BUQ8)
Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD)
Gene: DDX23

Interactor 2: LSM5 (Q9Y4Y9)
U6 snRNA-associated Sm-like protein LSm5
Gene: LSM5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 820 Hs			1 91
+	Hs
		911733 DDX23_HUMAN (1-820): 5.19e-160: 488: 100.00		RUXE_HUMAN (1-84): 8.29e-27: 95.4: 26.37
+	Hs
		1313213 DDX23_HUMAN (1-820): 5.19e-160: 488: 100.00		LSM7_HUMAN (7-91): 7.4e-18: 73: 21.11
+	Hs
		912103 DDX23_HUMAN (1-820): 5.19e-160: 488: 100.00		RUXG_HUMAN (10-82): 1.17e-12: 59.2: 26.03
+	Hs
		68454 DDX23_HUMAN (1-820): 5.19e-160: 488: 100.00		RUXGL_HUMAN (10-82): 2.1e-11: 56.1: 26.03
+	Hs
		911765 DDX41_HUMAN (365-795): 7.12e-81: 273: 39.32		RUXE_HUMAN (1-84): 8.29e-27: 95.4: 26.37