HitPredict - High confidence protein-protein interactions

Interactor 1: RN126 (Q9BV68)
E3 ubiquitin-protein ligase RNF126 (EC 2.3.2.27) (RING finger protein 126)
Gene: RNF126

Interactor 2: RN126 (Q9BV68)
E3 ubiquitin-protein ligase RNF126 (EC 2.3.2.27) (RING finger protein 126)
Gene: RNF126

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	1.00	0.885

Property	Details
Experiments	29167269, 33607208, 23026136, 23418353
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	zf-RING_2~zf-RING_2
Common GO terms	GO:0005154 - epidermal growth factor receptor binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 16 others more... GO:0006511 - ubiquitin-dependent protein catabolic process GO:0006513 - protein monoubiquitination GO:0016567 - protein ubiquitination GO:0035519 - protein K29-linked ubiquitination GO:0042059 - negative regulation of epidermal growth factor receptor signaling pathway GO:0042127 - regulation of cell population proliferation GO:0042147 - retrograde transport, endosome to Golgi GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043162 - ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO:0044314 - protein K27-linked ubiquitination GO:0046872 - metal ion binding GO:0061630 - ubiquitin protein ligase activity GO:0070534 - protein K63-linked ubiquitination GO:0070936 - protein K48-linked ubiquitination GO:0071629 - cytoplasm protein quality control by the ubiquitin-proteasome system GO:1905168 - positive regulation of double-strand break repair via homologous recombination
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1	311
Hs

1	311

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Last updated: 15 Jul 2024