Protein: SEPT7
Septin-7 (CDC10 protein homolog)

Gene: SEPT7, SEPTIN7
Organism: Homo sapiens
Interactions: 169
UniProt ID: Q16181

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0001725 - stress fiber
GO:0003924 - GTPase activity
GO:0005198 - structural molecule activity
GO:0005525 - GTP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1121181

SEPT6
Septin-6

13

19

Small-scale

0.980

High

1156425

SEP11
Septin-11

12

20

High-throughput

0.977

High

1156427

SEP10
Septin-10

9

20

High-throughput

0.973

High

1156433

SEPT9
Septin-9

9

20

Small-scale

0.971

High

1136967

SEPT2
Septin-2

8

19

Small-scale

0.968

High

1156399

SEPT8
Septin-8

8

20

High-throughput

0.967

High

1156411

SEPT5
Septin-5

5

20

Small-scale

0.930

High

1156431

SEPT3
Neuronal-specific septin-3

5

20

High-throughput

0.925

High

1156390

SEP12
Septin-12

5

20

Small-scale

0.923

High

1156396

SEPT1
Septin-1

3

20

High-throughput

0.861

High

1156383

SEP14
Septin-14

3

20

Small-scale

0.858

High

210495

SEPT4
Septin-4

3

20

High-throughput

0.855

High

1156369

SEPT7
Septin-7

1

20

Small-scale

0.692

High

1156417

BORG4
Cdc42 effector protein 4

4

15

High-throughput

0.691

High

1156423

ANLN
Anillin

3

12

High-throughput

0.656

High

1145858

RBP1
RalA-binding protein 1

3

4

High-throughput

0.633

High

563823

CFTR
Cystic fibrosis transmembrane conductance regulator

2

3

High-throughput

0.611

High

843591

HD
Huntingtin

2

8

High-throughput

0.588

High

241795

PRKN
E3 ubiquitin-protein ligase parkin

2

11

High-throughput

0.584

High

375555

RASK
GTPase KRas

2

20

High-throughput

0.584

High

537226

HSP7C
Heat shock cognate 71 kDa protein

2

2

High-throughput

0.584

High

914620

RM12
Large ribosomal subunit protein bL12m

2

9

High-throughput

0.574

High

1048863

REL
Proto-oncogene c-Rel

1

2

High-throughput

0.573

High

934668

TERA
Transitional endoplasmic reticulum ATPase

2

5

High-throughput

0.571

High

1156428

HDAC6
Protein deacetylase HDAC6

1

4

Small-scale

0.561

High

529872

TAU
Microtubule-associated protein tau

2

15

Small-scale

0.552

High

1156393

DOCK8
Dedicator of cytokinesis protein 8

2

0

High-throughput

0.547

High

340139

PCNT
Pericentrin

1

10

High-throughput

0.541

High

158219

COPE
Coatomer subunit epsilon

1

4

High-throughput

0.536

High

484547

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.536

High

535110

BIP
Endoplasmic reticulum chaperone BiP

1

8

High-throughput

0.536

High

637533

FLNA
Filamin-A

1

5

High-throughput

0.536

High

773521

COPB2
Coatomer subunit beta'

1

9

High-throughput

0.536

High

1111013

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.536

High

1156410

TGS1
Trimethylguanosine synthase

1

3

High-throughput

0.536

High

1156416

CPVL
Probable serine carboxypeptidase CPVL

1

4

High-throughput

0.536

High

161477

KMT2D
Histone-lysine N-methyltransferase 2D

1

6

High-throughput

0.515

High

158727

BORG1
Cdc42 effector protein 2

1

15

Small-scale

0.501

High

185735

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

3

High-throughput

0.501

High

1156434

BORG2
Cdc42 effector protein 3

1

15

Small-scale

0.501

High

1156426

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.493

High

1156430

STAP2
Signal-transducing adaptor protein 2

1

0

High-throughput

0.493

High

1156408

ACAP3
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3

1

10

High-throughput

0.489

High

1035509

CENPE
Centromere-associated protein E

1

1

Small-scale

0.481

High

156633

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

3

High-throughput

0.479

High

172856

XPO1
Exportin-1

1

13

High-throughput

0.479

High

176201

PER2
Period circadian protein homolog 2

1

2

Small-scale

0.479

High

189586

STX7
Syntaxin-7

1

5

High-throughput

0.479

High

247930

NUPR1
Nuclear protein 1

1

3

High-throughput

0.479

High

256869

H2B1K
Histone H2B type 1-K

1

5

High-throughput

0.479

High

260009

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.479

High

299216

FLOT1
Flotillin-1

1

4

High-throughput

0.479

High

302538

RNF8
E3 ubiquitin-protein ligase RNF8

1

5

Small-scale

0.479

High

318788

RHBT1
Rho-related BTB domain-containing protein 1

1

10

High-throughput

0.479

High

341064

DIRA3
GTP-binding protein Di-Ras3

1

4

High-throughput

0.479

High

372132

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

373948

RASN
GTPase NRas

1

20

High-throughput

0.479

High

374624

RASH
GTPase HRas

1

19

High-throughput

0.479

High

440091

LCK
Tyrosine-protein kinase Lck

1

2

High-throughput

0.479

High

445899

ENOA
Alpha-enolase

1

1

High-throughput

0.479

High

463540

LYN
Tyrosine-protein kinase Lyn

1

2

High-throughput

0.479

High

556109

CADH1
Cadherin-1

1

2

High-throughput

0.479

High

558168

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.479

High

562071

LAMP2
Lysosome-associated membrane glycoprotein 2

1

4

High-throughput

0.479

High

565398

ITA4
Integrin alpha-4

1

4

High-throughput

0.479

High

588801

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

606817

CEBPB
CCAAT/enhancer-binding protein beta

1

6

High-throughput

0.479

High

695568

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

715604

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.479

High

731336

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.479

High

754859

H2B1B
Histone H2B type 1-B

1

5

High-throughput

0.479

High

791418

SYUA
Alpha-synuclein

1

7

High-throughput

0.479

High

799152

BRCA1
Breast cancer type 1 susceptibility protein

1

6

High-throughput

0.479

High

830810

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

872370

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.479

High

897839

CDK9
Cyclin-dependent kinase 9

1

6

High-throughput

0.479

High

898470

PPT1
Palmitoyl-protein thioesterase 1

1

1

High-throughput

0.479

High

900836

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.479

High

955214

CDC42
Cell division control protein 42 homolog

1

13

High-throughput

0.479

High

956310

RAB2A
Ras-related protein Rab-2A

1

2

High-throughput

0.479

High

975057

ARF6
ADP-ribosylation factor 6

1

5

High-throughput

0.479

High

978034

RHOB
Rho-related GTP-binding protein RhoB

1

15

High-throughput

0.479

High

980795

H2B1C
Histone H2B type 1-C/E/F/G/I

1

5

High-throughput

0.479

High

995620

ACTC
Actin, alpha cardiac muscle 1

1

2

High-throughput

0.479

High

1025463

CDK5
Cyclin-dependent kinase 5

1

5

High-throughput

0.479

High

1106915

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

High-throughput

0.479

High

1107753

SQSTM
Sequestosome-1

1

2

High-throughput

0.479

High

1144922

RAB35
Ras-related protein Rab-35

1

2

High-throughput

0.479

High

1156372

PKHG4
Puratrophin-1

1

1

High-throughput

0.479

High

1156375

TET5C
Terminal nucleotidyltransferase 5C

1

1

High-throughput

0.479

High

1156376

MLIP
Muscular LMNA-interacting protein

1

5

High-throughput

0.479

High

1156378

VIR
Protein virilizer homolog

1

4

High-throughput

0.479

High

1156381

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

6

High-throughput

0.479

High

1156384

MOB3C
MOB kinase activator 3C

1

3

High-throughput

0.479

High

1156386

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.479

High

1156387

ZN598
E3 ubiquitin-protein ligase ZNF598

1

1

High-throughput

0.479

High

1156389

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

1156394

BICD2
Protein bicaudal D homolog 2

1

7

High-throughput

0.479

High

1156395

PARD3
Partitioning defective 3 homolog

1

4

High-throughput

0.479

High

1156397

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

3

High-throughput

0.479

High

1156398

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

1156400

ESR2
Estrogen receptor beta

1

12

High-throughput

0.479

High

1156401

PRCC
Proline-rich protein PRCC

1

1

High-throughput

0.479

High

1156403

SH3K1
SH3 domain-containing kinase-binding protein 1

1

7

High-throughput

0.479

High

1156405

LRCH3
DISP complex protein LRCH3

1

7

High-throughput

0.479

High

1156409

FMNL2
Formin-like protein 2

1

2

High-throughput

0.479

High

1156415

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

4

High-throughput

0.479

High

1156421

GORS2
Golgi reassembly-stacking protein 2

1

4

High-throughput

0.479

High

1156422

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

1

High-throughput

0.479

High

1156429

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1156435

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.479

High

1156436

SRRM2
Serine/arginine repetitive matrix protein 2

1

4

High-throughput

0.479

High

1156439

RRP44
Exosome complex exonuclease RRP44

1

1

High-throughput

0.479

High

1156440

SHLB1
Endophilin-B1

1

3

High-throughput

0.479

High

1156441

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.479

High

1156442

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

2

High-throughput

0.479

High

126116

AP3B1
AP-3 complex subunit beta-1

1

0

Small-scale

0.458

High

190148

TNC18
Trinucleotide repeat-containing gene 18 protein

1

0

High-throughput

0.458

High

327274

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

423660

ARGI1
Arginase-1

1

0

High-throughput

0.458

High

604000

CXA1
Gap junction alpha-1 protein

1

0

High-throughput

0.458

High

718820

CCND2
G1/S-specific cyclin-D2

1

0

Small-scale

0.458

High

925928

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.458

High

964011

COPZ1
Coatomer subunit zeta-1

1

0

High-throughput

0.458

High

970571

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

979727

H4
Histone H4

1

0

High-throughput

0.458

High

1013139

SARNP
SAP domain-containing ribonucleoprotein

1

0

High-throughput

0.458

High

1156374

ARM12
Armadillo repeat-containing protein 12

1

0

Small-scale

0.458

High

1156402

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.458

High

1156407

CEP20
Centrosomal protein 20

1

0

High-throughput

0.458

High

1156414

RHG39
Rho GTPase-activating protein 39

1

0

High-throughput

0.458

High

1156438

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.458

High

1056752

FMR1
Fragile X messenger ribonucleoprotein 1

1

3

High-throughput

0.457

High

150

A0A024R6X4
PLEKHG4

1

1

High-throughput

0.445

High

442944

PRGR
Progesterone receptor

1

11

Small-scale

0.445

High

619819

VCAM1
Vascular cell adhesion protein 1

1

3

High-throughput

0.445

High

890657

RGS3
Regulator of G-protein signaling 3

1

9

High-throughput

0.445

High

1130275

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

3

High-throughput

0.445

High

1156404

OTUB1
Ubiquitin thioesterase OTUB1

1

1

High-throughput

0.445

High

1156424

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

106001

APRIO
Alternative prion protein

1

8

High-throughput

0.437

High

642895

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

2

High-throughput

0.437

High

768293

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

1156370

E2F4
Transcription factor E2F4

1

1

High-throughput

0.437

High

1156377

DCA15
DDB1- and CUL4-associated factor 15

1

3

High-throughput

0.437

High

1156379

SCYL2
SCY1-like protein 2

1

2

High-throughput

0.437

High

1156382

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.437

High

1156385

ASXL2
Putative Polycomb group protein ASXL2

1

4

High-throughput

0.437

High

1156391

UBR7
Putative E3 ubiquitin-protein ligase UBR7

1

1

High-throughput

0.437

High

1156392

UN13C
Protein unc-13 homolog C

1

4

High-throughput

0.437

High

1156413

ASXL3
Putative Polycomb group protein ASXL3

1

6

High-throughput

0.437

High

1156418

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

1156432

CHRD1
Cysteine and histidine-rich domain-containing protein 1

1

2

High-throughput

0.437

High

1156437

LAMP3
Lysosome-associated membrane glycoprotein 3

1

4

High-throughput

0.437

High

255042

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.407

High

1156420

VIAAT
Vesicular inhibitory amino acid transporter

1

4

High-throughput

0.407

High

811290

GRIK1
Glutamate receptor ionotropic, kainate 1

1

0

High-throughput

0.282

High

65762

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

0

High-throughput

0.269

Low

1009760

M3K9
Mitogen-activated protein kinase kinase kinase 9

1

0

High-throughput

0.269

Low

1068800

R51A2
RAD51-associated protein 2

1

0

High-throughput

0.249

Low

1156371

OCLN
Occludin

1

0

High-throughput

0.249

Low

1156373

FRPD3
FERM and PDZ domain-containing protein 3

1

0

High-throughput

0.249

Low

1156380

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1156419

ESF1
ESF1 homolog

1

0

High-throughput

0.249

Low

1155055

UT2
Urea transporter 2

1

0

High-throughput

0.232

Low

1156388

SYT12
Synaptotagmin-12

1

0

High-throughput

0.232

Low

1156406

S45A3
Solute carrier family 45 member 3

1

0

High-throughput

0.232

Low

1156412

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025