HitPredict

Interactor 1: IMA4 (O00505)
Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3) (SRP1-gamma)
Gene: KPNA3

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27609421, 14743216
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 521 Hs			1 551
+	Hs
		134880 IMA3_HUMAN (1-521): 1.68e-160: 468: 85.80		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		853247 IMA1_HUMAN (3-521): 1.35e-143: 425: 48.49		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		238660 IMA7_HUMAN (1-520): 9.33e-140: 415: 46.54		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		853573 IMA5_HUMAN (5-520): 3.45e-133: 398: 45.52		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		131378 IMA4_HUMAN (1-521): 9.9e-164: 476: 100.00		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		587478 IMA1_HUMAN (3-521): 1.35e-143: 425: 48.49		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		853242 IMA1_HUMAN (3-521): 1.35e-143: 425: 48.49		RELB_HUMAN (3-461): 2.62e-154: 455: 40.00
+	Hs
		238659 IMA7_HUMAN (1-520): 9.33e-140: 415: 46.54		RELB_HUMAN (3-461): 2.62e-154: 455: 40.00
+	Hs
		853571 IMA5_HUMAN (5-520): 3.45e-133: 398: 45.52		RELB_HUMAN (3-461): 2.62e-154: 455: 40.00