Interactor 1: LGR4 (Q9BXB1)
Leucine-rich repeat-containing G-protein coupled receptor 4 (G-protein coupled receptor 48)
Gene: LGR4

Interactor 2: RSPO3 (Q9BXY4)
R-spondin-3 (Protein with TSP type-1 repeat) (hPWTSR) (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2)
Gene: RSPO3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.845

The method score is based on:

Property Details
Experiments 25504990, 29752411, 24050775
Identification Methods pull down, fluorescent resonance energy transfer
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Furin-like_2~LRR_8
Common GO terms GO:0090263 - positive regulation of canonical Wnt signaling pathway
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 951
Hs

1 272
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024