HitPredict

Interactor 1: OSB10 (Q9BXB5)
Oxysterol-binding protein-related protein 10 (ORP-10) (OSBP-related protein 10)
Gene: OSBPL10

Interactor 2: VAPA (Q9P0L0)
Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)
Gene: VAPA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

Property	Details
Experiments	26496610, 28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 764 Hs			1 249
+	Hs
		310785 OSB10_HUMAN (1-764): 0: 752: 100.00		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		1315187 OSB11_HUMAN (20-762): 0: 682: 53.94		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		310784 OSB11_HUMAN (20-762): 0: 682: 53.94		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		1302540 OSBL9_HUMAN (74-762): 0: 625: 34.51		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		310768 OSBL9_HUMAN (74-762): 0: 625: 34.51		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		1282120 OSBP2_HUMAN (12-763): 0: 545: 18.42		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Rn
		1225298 OSBL1_RAT (77-762): 3.61e-177: 534: 18.17		VAPA_RAT (1-249): 3.22e-99: 291: 96.79
+	Hs
		1315823 OSBL1_HUMAN (77-762): 1.4e-176: 532: 18.01		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		603095 OSBP1_HUMAN (77-762): 9.42e-168: 505: 19.09		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		310745 OSBP2_HUMAN (12-763): 0: 545: 18.42		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		310786 OSBL1_HUMAN (77-762): 1.4e-176: 532: 18.01		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	At
		1258327 ORP2A_ARATH (27-763): 0: 547: 18.09		VAP11_ARATH (8-214): 4.22e-67: 210: 25.11
+	Hs
		310506 OSBP1_HUMAN (77-762): 9.42e-168: 505: 19.09		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		1245667 OSBL1_HUMAN (77-762): 1.4e-176: 532: 18.01		MSPD2_HUMAN (14-190): 1.24e-39: 144: 19.34
+	Dm
		1362486 Q9VC05_DROME (62-763): 1.2e-166: 502: 18.51		Q9W4N8_DROME (15-216): 1.28e-52: 173: 37.56
+	Hs
		310791 OSBL8_HUMAN (212-762): 7.09e-133: 417: 27.20		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		1122072 OSBL2_HUMAN (340-762): 7.1e-135: 409: 18.98		Q53XM7_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		310803 OSBL2_HUMAN (340-762): 7.1e-135: 409: 18.98		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Dm
		1362484 Q9VC05_DROME (62-763): 1.2e-166: 502: 18.51		Q9VSD3_DROME (11-201): 1.14e-46: 156: 29.02
+	Hs
		603075 OSBP1_HUMAN (77-762): 9.42e-168: 505: 19.09		MSPD2_HUMAN (14-190): 1.24e-39: 144: 19.34