Interactor 1: CAR11 (Q9BXL7)
Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 1) (Carma 1)
Gene: CARD11

Interactor 2: NEMO (Q9Y6K9)
NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.656

The method score is based on:

Property Details
Experiments 15184390, 18625728, 17363905
Identification Methods pull down, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007249 - canonical NF-kappaB signal transduction
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0050862 - positive regulation of T cell receptor signaling pathway
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1154
Hs

1 419
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024