HitPredict

Interactor 1: STK25 (O00506)
Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)
Gene: STK25

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 426 Hs			1 246
+	Hs
		131562 STK25_HUMAN (1-426): 4.51e-156: 449: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	At
		965360 CIPKC_ARATH (8-419): 2.89e-137: 403: 20.14		14332_ARATH (1-241): 4.75e-145: 407: 63.27
+	At
		1280891 CIPKC_ARATH (8-419): 2.89e-137: 403: 20.14		14337_ARATH (1-239): 1.25e-144: 406: 61.73
+	At
		788672 CIPKC_ARATH (8-419): 2.89e-137: 403: 20.14		14333_ARATH (3-241): 4.44e-143: 402: 62.96
+	Hs
		681770 AKT1_HUMAN (6-330): 4.86e-131: 387: 25.75		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		568616 KAPCA_HUMAN (4-322): 7.9e-132: 384: 22.32		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		681776 AKT1_HUMAN (6-330): 4.86e-131: 387: 25.75		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		909512 STK3_HUMAN (2-295): 3.42e-128: 380: 51.01		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683316 STK3_HUMAN (2-295): 3.42e-128: 380: 51.01		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		909502 STK4_HUMAN (3-284): 1.11e-127: 379: 52.80		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683308 STK4_HUMAN (3-284): 1.11e-127: 379: 52.80		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		568620 KAPCA_HUMAN (4-322): 7.9e-132: 384: 22.32		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		610682 KAPCB_HUMAN (4-315): 1.97e-131: 383: 23.75		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		646859 STK3_HUMAN (2-295): 3.42e-128: 380: 51.01		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		646852 STK4_HUMAN (3-284): 1.11e-127: 379: 52.80		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		681766 AKT1_HUMAN (6-330): 4.86e-131: 387: 25.75		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		904517 STK3_HUMAN (2-295): 3.42e-128: 380: 51.01		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		904507 STK4_HUMAN (3-284): 1.11e-127: 379: 52.80		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		981974 STK3_HUMAN (2-295): 3.42e-128: 380: 51.01		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		681682 AKT1_HUMAN (6-330): 4.86e-131: 387: 25.75		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62